TISSUE-SPECIFIC GENERATION OF 2 PRE-PROTACHYKININ MESSENGER-RNAS FROM ONE GENE BY ALTERNATIVE RNA SPLICING
TISSUE-SPECIFIC GENERATION OF 2 PRE-PROTACHYKININ MESSENGER-RNAS FROM ONE GENE BY ALTERNATIVE RNA SPLICING
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DOI：
10.1038/312729a0
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发表时间：
1984-01-01
期刊：
影响因子：
64.8
通讯作者：
NAKANISHI, S
中科院分区：
文献类型：
--
作者：
NAWA, H;KOTANI, H;NAKANISHI, S
A novel mammalian neuropeptide, the tachykinin substance K, is specified by a discrete genomic segment. Alternative RNA splicing generates 2 distinct mRNA encoding the neuropeptide substance P alone or with substance K from a single preprotachykinin gene. Relative amounts of the mRNA vary in different tissues, suggesting that the substance K-encoding sequence is regulated in a tissue-specific manner.
