The genome sequence and structure of rice chromosome 1
The genome sequence and structure of rice chromosome 1
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DOI：
10.1038/nature01184
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发表时间：
2002-11-21
期刊：
影响因子：
64.8
通讯作者：
Gojohori, T
中科院分区：
文献类型：
--
作者：
Sasaki, T;Matsumoto, T;Gojohori, T
水稻因其基因组小、遗传图谱广泛、转化相对容易、与其他粮食作物同源(1-4)而被认为是模式植物。在这里，我们报道了水稻基因组中最长的1号染色体的基本完整的序列。我们总结了染色体结构的特点和从序列中获得的生物学见解。对43.3兆碱基(Mb)的非重叠序列的分析揭示了6756个蛋白质编码基因，其中3161个与另一模式植物拟南芥的蛋白质同源。大约30%(2,073)的基因已经被功能分类。水稻1号染色体富含(G+C)，特别是在其编码区，其特点是由分散或以串联重复排列的多个基因家族组成。与草稿序列(5)的比较表明高质量完成序列的重要性。
The rice species Oryza sativa is considered to be a model plant because of its small genome size, extensive genetic map, relative ease of transformation and synteny with other cereal crops(1-4). Here we report the essentially complete sequence of chromosome 1, the longest chromosome in the rice genome. We summarize characteristics of the chromosome structure and the biological insight gained from the sequence. The analysis of 43.3 megabases (Mb) of non-overlapping sequence reveals 6,756 protein coding genes, of which 3,161 show homology to proteins of Arabidopsis thaliana, another model plant. About 30% ( 2,073) of the genes have been functionally categorized. Rice chromosome 1 is (G + C)-rich, especially in its coding regions, and is characterized by several gene families that are dispersed or arranged in tandem repeats. Comparison with a draft sequence(5) indicates the importance of a high-quality finished sequence.