Aggressive angiomyxoma of childhood: Two unusual cases developed in the scrotum

Aggressive angiomyxoma of childhood: Two unusual cases developed in the scrotum
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DOI:
10.1007/s10024-001-0255-3
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发表时间:
2003-03-01
影响因子:
1.9
通讯作者:
Chi, JG
Chi, JG
中科院分区:
医学4区
文献类型:
--
作者:
Kim, HS;Park, SH;Chi, JG

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侵袭性血管粘液瘤(AAM)是一种局部浸润性软组织肿瘤,主要见于女性骨盆和会阴。AAM在成年和青少年男性中的发病率较低,在男性儿童中非常罕见。然而,2例AAM发生在8岁和1岁男孩的阴囊。肉眼可见,两个肿瘤均为轮廓不清的结节,切面呈粘液样均匀分叶状。病例2阴囊被增生肿块所取代,呈息肉样外观。镜检均可见细胞下黏液样基质、梭形和星状基质细胞,以及不同口径的血管。这两种病变典型表现为浸润性边界并渗透到皮肤附件。和达多斯的肌肉纤维。在儿童时期发现的阴囊肿块的鉴别诊断中应考虑AAM。
Aggressive angiomyxoma (AAM) is a locally invasive soft tissue tumor and is predominantly found in the female pelvis and perineum. The incidence of AAM in adult and adolescent males is low, and is very rare in male children. However, two cases of AAM occur-red in the scrotum of 8-year-old and 1-year-old boys. Grossly, both tumors were ill-delineated nodules showing myxoid homogenous and lobulated cut surface. The scrotum of case 2 was replaced by the exuberant mass, making a polypoid appearance. On microscopic examination, both had hypocellular myxoid stroma, spindle and stellate stromal cells, and blood vessels of various calibers. Both lesions typically showed infiltrating borders an penetrated into skin adnexa. and Dartos' muscle fibers. AAM should be considered in the differential diagnosis of a scrotal mass found in childhood.