High prevalence of GB virus-C/hepatitis G virus infection in liver transplant recipients.
High prevalence of GB virus-C/hepatitis G virus infection in liver transplant recipients.
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肝移植受者中 GB 病毒-C/庚型肝炎病毒感染的患病率较高。
DOI：
10.1097/00007890-199706150-00028
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发表时间：
1997
期刊：
影响因子：
6.2
通讯作者：
Lau,JY
中科院分区：
文献类型：
--
作者：
Dickson,RC;Qian,KP;Lau,JY
背景：为了确定非丙型肝炎病毒适应症的肝移植受者中GB病毒-C/庚型肝炎病毒(GBV-C/HGV)感染的流行率，44名患者接受了隐源性、自身免疫性、乙肝、方法：采用逆转录聚合酶链式反应(RT-PCR)检测HGVRNA。结果：胆汁淤积性肝病患者肝移植后GBV-C/HGVRNA阳性率明显高于对照组(28/44例[%]对13/91例[14%]；P<；0.001)。GBV-C/HGV感染与输血产品的数量、特定的外科医生或特定的肝病无关。结论：我们得出结论：GBV-C/HGV感染在肝移植受者中非常常见，但在这一人群中临床影响很小。
Background.To determine the prevalence of GB virus-C/hepatitis G virus (GBV-C/HGV) infection in liver transplant recipients transplanted for non-hepatitis C virus indications, 44 patients transplanted for cryptogenic, autoimmune, hepatitis B, or cholestatic liver disease and 91 non-liver transplantation (LT) patients with similar diagnoses seen in the same study period (control group) were studied.Methods.HGV RNA was detected by reverse transcription polymerase chain reaction with primers from the 5′-untranslated region.Results.GBV-C/HGV RNA was commonly detected in post-LT patients compared with the control group (28/44 [64%] vs. 13/91 [14%]; P< 0.001). GBV-C/HGV infection was not related to the number of blood products transfused, a particular surgeon, or a specific liver disease. GBV-C/HGV infection also had no significant impact on the post-LT clinical profile.Conclusions.We conclude that GBV-C/HGV infection is very common in LT recipients, but that it has minimal clinical impact in this population.
用于检测人类隐源性肝炎中 GB 病毒 C 的共有寡核苷酸引物。
影响因子：
3.1
作者：
T. Leary;A. Muerhoff;J. Simons;T. Pilot;J. C. Erker;M. Chalmers;G. Schlauder;G. Dawson;S. Desai;I. Mushahwar
通讯作者：
I. Mushahwar
影响因子：
13.5
作者：
DAVIS, GL;LAU, JYN;ALBRECHT, J
通讯作者：
ALBRECHT, J