An automated method for preparation of [(18)F]sodium fluoride for injection, USP to address the technetium-99m isotope shortage.

An automated method for preparation of [(18)F]sodium fluoride for injection, USP to address the technetium-99m isotope shortage.
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DOI:
10.1016/j.apradiso.2009.08.012
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发表时间:
2010-01
影响因子:
1.6
通讯作者:
Scott, Peter J. H.
Scott, Peter J. H.
中科院分区:
工程技术3区
文献类型:
--
作者:
Hockley, Brian G.;Scott, Peter J. H.

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由于世界范围内锝-99m短缺,迫切需要获得[18F]氟化钠用于骨转移的PET成像。为了促进诊断核医学成像程序中[18 F]氟化钠的全球可用性,提出了一种使用改良的GE Tracerlab FX-FN快速生产注射用[18 F]氟化钠(USP)的简单方法。
The worldwide shortage of technetium-99m has created an immediate and urgent need for access to [18F]sodium fluoride for PET imaging of bone metastasis. In order to facilitate global availability of [18F]sodium fluoride for diagnostic nuclear medicine imaging procedures, a straightforward method for rapid production of [18F]sodium fluoride for injection, USP, using a modified GE Tracerlab FX-FN is presented.
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