Prevalence of open-angle glaucoma and ocular hypertension in Latinos - The Los Angeles Latino Eye Study
Prevalence of open-angle glaucoma and ocular hypertension in Latinos - The Los Angeles Latino Eye Study
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DOI：
10.1016/j.ophtha.2004.01.025
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发表时间：
2004-08-01
期刊：
影响因子：
13.7
通讯作者：
Azen, SP
中科院分区：
文献类型：
--
作者：
Varma, R;Mei, YL;Azen, SP
目的：目的：评估拉丁美洲成年人高眼压和开角型青光眼（OAG）的年龄和性别特异性患病率。设计：基于人群的横断面研究。参与者：来自加州洛杉矶6个人口普查区的6357名40岁及以上的拉丁美洲人。方法：研究队列由居住在加州拉蓬特6个人口普查区的40岁及以上的所有自我认定的主要是墨西哥血统的拉丁美洲人组成。所有参与者都接受了完整的眼科检查，包括测量眼内压（IOP），使用自动视野分析仪进行视野（VF）测试，以及同时进行视盘立体眼底摄影。高眼压定义为IOP>21 mmHg且无视盘损伤或VF测试结果异常。开角型青光眼定义为存在开角型青光眼，并且有各种标准，包括至少一只眼睛存在青光眼VF异常和/或青光眼视盘损伤的证据。主要结果测量：开角型青光眼和高眼压的患病率。6142名参与者在临床中心接受了完整的眼科检查，OAG的患病率为4.74%（95%置信区间[CI]，4.22%-5.30%）。高眼压的患病率为3.56%（95%CI，3.12%~ 4.06%）。老年拉美人OAG和高眼压的患病率高于年轻拉美人（P
Objective: To estimate age- and gender-specific prevalences of ocular hypertension and open-angle glaucoma (OAG) in adult Latinos.Design: Population-based, cross-sectional study.Participants: Six thousand three hundred fifty-seven Latinos 40 years and older from 6 census tracts in Los Angeles, California.Methods: The study cohort consisted of all self-identified Latinos of primarily Mexican ancestry 40 years and older residing in 6 census tracts in La Puente, California. All participants underwent a complete ophthalmologic examination, including measurement of intraocular pressure (IOP), visual field (VF) testing using an automated field analyzer, and simultaneous stereoscopic fundus photography of the optic disc. Ocular hypertension was defined as IOP of >21 mmHg and the absence of optic disc damage or abnormal VF test results. Open-angle glaucoma was defined as the presence of an open angle and various criteria that included a glaucomatous VF abnormality and/or evidence of glaucomatous optic disc damage in at least one eye.Main Outcome Measures: Prevalence of open-angle glaucoma and ocular hypertension.Results: For the 6142 participants who underwent a complete ophthalmologic examination at the clinical center, the prevalence of OAG was 4.74% (95% confidence interval [CI], 4.22%-5.30%). The prevalence of ocular hypertension was 3.56% (95% CI, 3.12%-4.06%). The prevalences of OAG and ocular hypertension were higher in older Latinos than in younger Latinos (P