Haplotype Inference.
Haplotype Inference.
复制标题
单倍型推断。
DOI:
10.1007/978-1-4939-7274-6_23
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发表时间:
2017
期刊:
影响因子:
--
通讯作者:
Li,Jing
中科院分区:
文献类型:
--
作者:
Song,Sunah;Li,Xin;Li,Jing
Haplotypes, as they specify linkage patterns between individual nucleotide variants, confer critical information for understanding the genetics of human diseases. However, haplotype information is not directly obtainable from high-throughput genotyping platforms. In this chapter, we introduce four representative methods to reconstruct haplotypes from unphased genotype data, two of them are for unrelated individuals and the other two are for families.