Haplotype Inference.

Haplotype Inference.
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单倍型推断。

DOI:
10.1007/978-1-4939-7274-6_23
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发表时间:
2017
期刊:
Methods in molecular biology (Clifton, N.J.)
影响因子:
--
通讯作者:
Li,Jing
Li,Jing
中科院分区:
--
文献类型:
--
作者:
Song,Sunah;Li,Xin;Li,Jing

文献摘要

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Haplotypes, as they specify linkage patterns between individual nucleotide variants, confer critical information for understanding the genetics of human diseases. However, haplotype information is not directly obtainable from high-throughput genotyping platforms. In this chapter, we introduce four representative methods to reconstruct haplotypes from unphased genotype data, two of them are for unrelated individuals and the other two are for families.