Increase in the share of steady partners as a source of HIV infection: a 17-year study of seroconversion among gay men
Increase in the share of steady partners as a source of HIV infection: a 17-year study of seroconversion among gay men
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DOI：
10.1097/00002030-200107060-00013
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发表时间：
2001-07-06
期刊：
影响因子：
3.8
通讯作者：
Coutinho, R
中科院分区：
文献类型：
--
作者：
Davidovich, U;de Wit, J;Coutinho, R
目的：为了研究的份额稳定与休闲的合作伙伴之间的艾滋病毒感染源的男同性恋者血清转换1984年和2000年之间的艾滋病毒transmissions.Methods的来源，在血清转换的年龄的影响：样本包括144 seroconverstors从阿姆斯特丹队列研究同性恋男性。结果：分析发现，历年和血清转换年龄之间存在交互作用（P < 0.05）。年轻的血清转换者在艾滋病流行后期被其稳定伴侣感染的优势比（优势比，11.33; 95%置信区间，1.77-72.13）更高：1984年至1987年为15%（20人中有3人），1994年至2000年为67%（9人中有6人）。对于年龄较大的血清转换者来说，没有这样的时间效应，他们更有可能被临时伴侣感染：79% 1984年至1987年，47人中有37人，83%（15/18）。结论：如今，年轻的同性恋血清转换者更有可能从稳定的伴侣那里感染艾滋病毒，而不是从临时伴侣那里，与艾滋病流行早期相比，也与年龄较大的同性恋血清转换者相比。迫切需要采取预防措施，解决年轻男同性恋者稳定关系中的性风险行为。(C)2001年利平科特威廉姆斯&威尔金斯。
Objectives: To examine the share of steady versus casual partners as the source of HIV infection in gay male seroconversions between 1984 and 2000 and the effect of age at seroconversion on the source of HIV transmission.Methods: The sample consisted of 144 seroconverstors from the Amsterdam Cohort Study among Homosexual Men. Questionnaires and post-seroconversion interviews were used to determine the source of HIV transmission.Results: Analysis revealed an interaction effect between calendar year and age at seroconversion (P < 0.05). Younger seroconverters had higher odds ratios [odds ratio, 11.33; 95% confidence interval, 1.77-72.13] to be infected by their steady partner late in the AIDS epidemic: 15% (three of 20) between 1984 and 1987 versus 67% (six of nine) between 1994 and 2000. No such time effect was present for older seroconverters who were consistently more likely to be infected by a casual partner: 79% (37 of 47) between 1984 and 1987, and 83% (15 of 18) between 1994 and 2000.Conclusions: Young gay seroconverters today are more likely to have contracted HIV from a steady partner than from a casual partner, compared with early in the AIDS epidemic and compared also with older gay seroconverters. There is a pressing need for preventive measures addressing sexual risk behaviour within steady relationships among younger gay men. (C) 2001 Lippincott Williams & Wilkins.