Pd-catalyzed Suzuki-Miyaura cross-coupling reactions between sulfamates and potassium Boc-protected aminomethyltrifluoroborates.

Pd-catalyzed Suzuki-Miyaura cross-coupling reactions between sulfamates and potassium Boc-protected aminomethyltrifluoroborates.
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DOI:
10.1021/ol401021x
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发表时间:
2013-05-17
期刊:
影响因子:
5.2
通讯作者:
Shin, Inji
Shin, Inji
中科院分区:
化学1区
文献类型:
--
作者:
Molander, Gary A.;Shin, Inji

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Sulfamates were studied as the electrophilic partners in the palladium-catalyzed Suzuki–Miyaura cross-coupling reaction with potassium Boc-protected primary and secondary aminomethyltrifluoroborates. A broad range of substrates was successfully coupled to provide the desired products. Complex molecules containing a new carbon-carbon bond and an aminomethyl moiety could be prepared through this developed method.
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