Ultrathin Gold Nanoribbons Synthesized within the Interior Cavity of a Self-Assembled Peptide Nanoarchitecture
Ultrathin Gold Nanoribbons Synthesized within the Interior Cavity of a Self-Assembled Peptide Nanoarchitecture
复制标题
DOI：
10.1021/la4044649
复制
发表时间：
2014-01-28
期刊：
影响因子：
3.9
通讯作者：
Imai, Takahito
中科院分区：
文献类型：
--
作者：
Tomizaki, Kin-ya;Wakizaka, Shota;Imai, Takahito
金纳米晶体由于其独特的物理、化学和生物相容性而受到越来越多的关注。为了开发一种模板辅助的方法用于制造金纳米晶体，我们在这里展示了从头设计和合成的β-折叠形成九肽（RU 006：Ac-AIAKAXKIA-NH 2，X = L-2-naphthylalanine），其经历自组装形成约100 nm宽和2.5 nm高的盘状纳米结构。这些自组装倾向于在超纯水中形成高阶组装网络。使用RU 006作为模板分子，我们在没有外部还原剂的情况下制备了宽50-100 nm、高2.5 nm和微米长的金纳米带。此外，为了确定纳米金形成的机制，我们合成了四种不同的RU 006类似物。基于使用RU 006和这些类似物获得的结果，我们提出了RU 006自组装的以下机理。首先，RU 006形成一个网络的合作协会的盘状组件在AuCl 4-离子的存在下，被封装和集中在网络架构的内腔。随后是电子从萘环转移到Au-III，导致在环境条件下缓慢生长，形成沿沿着模板网络结构的金纳米带。所得到的条带保持模板架构的腔的尺寸。我们的方法将允许不同的模板建筑形态的建设，并会发现在各种金属nanoarchitectures的建设中的应用。
There is increasing interest in gold nanocrystals due to their unique physical, chemical, and biocompatible properties. In order to develop a template-assisted method for the fabrication of gold nanocrystals, we demonstrate here the de novo design and synthesis of a beta-sheet-forming nonapeptide (RU006: Ac-AIAKAXKIA-NH2, X = L-2-naphthylalanine) which undergoes self-assembly to form disk-like nanoarchitectures approximately 100 nm wide and 2.5 nm high. These self-assemblies tend to form a network of higher-order assemblies in ultrapure water. Using RU006 as a template molecule, we fabricated ultrathin gold nanoribbons 50-100 nm wide, 2.5 nm high, and micrometers long without external reductants. Furthermore, in order to determine the mechanism of ultrathin gold nanoribbon formation, we synthesized four different RU006 analogues. On the basis of the results obtained using RU006 and these analogues, we propose the following mechanism for the self-assembly of RU006. First, RU006 forms a network by the cooperative association of disk-like assemblies in the presence of AuCl4- ions that are encapsulated and concentrated within the interior cavity of the network architectures. This is followed by electron transfer from the naphthalene rings to Au-III, resulting in slow growth to form ultrathin gold nanoribbons along the template network architectures under ambient conditions. The resulting ribbons retain the dimensions of the cavity of the template architecture. Our approach will allow the construction of diverse template architectural morphologies and will find applications in the construction of a variety of metallic nanoarchitectures.