Microvasculature of the human optic nerve.
Microvasculature of the human optic nerve.
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DOI：
10.1097/00041327-199603000-00079
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发表时间：
1995-07
影响因子：
4.2
通讯作者：
E. Onda;G. Cioffi;David R. Bacon;E. V. Van Buskirk
中科院分区：
文献类型：
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作者：
E. Onda;G. Cioffi;David R. Bacon;E. V. Van Buskirk
目的应用甲基丙烯酸甲酯血管腐蚀铸造技术对18只人眼正常前视神经微血管进行检测。方法选择视网膜中央动脉、睫状体后短动脉或两者同时插管，将甲基丙烯酸甲酯注入视神经前循环。组织型纤溶酶原激活剂预冲洗可溶解腔内凝块，大大增强微血管的充盈。结果视神经的浅神经纤维层主要由视网膜中央动脉供血。经短纤毛后动脉注射甲基丙烯酸甲酯的13只眼中，有11只眼在巩膜水平出现神经周、环状动脉吻合（锌-哈勒环）。这个圈的分支穿过视神经供应层前和层前区域以及乳头周围脉络膜。在没有这个动脉圈的两只眼睛中，睫状体后短动脉的直接分支支配前视神经。视神经前静脉引流几乎全部通过视网膜中央静脉及其分支。结论视神经前神经的主要供血动脉是短纤毛后动脉。与短后纤毛动脉的直接作用相比，乳头周围脉络膜对前视神经的作用是最小的。
PURPOSE Methyl methacrylate vascular corrosion casting techniques were used to examine the normal anterior optic nerve microvasculature in 18 human eye bank eyes. METHODS Selective cannulation of the central retinal artery, the short posterior ciliary arteries, or both, allowed the methyl methacrylate to be injected into the anterior optic nerve circulation. Preflushing with tissue plasminogen activator greatly enhanced the filling of the fine microvasculature by dissolving the intraluminal clots. RESULTS The superficial nerve fiber layer of the optic nerve received its primary blood supply from the central retinal artery. In 11 of 13 eyes injected with methyl methacrylate through the short posterior ciliary arteries, there was a perineural, circular arterial anastomosis (circle of Zinn-Haller) at the scleral level. Branches from this circle penetrated the optic nerve to supply the prelaminar and laminar regions and the peripapillary choroid. In the two eyes without this arterial circle, direct branches from the short posterior ciliary arteries supplied the anterior optic nerve. The venous drainage of the anterior optic nerve was almost entirely through the central retinal vein and its tributaries. CONCLUSIONS This study demonstrates that the main arterial vascular supply to the anterior optic nerve is from the short posterior ciliary arteries. The contribution of the peripapillary choroid to the anterior optic nerve is minimal in comparison to the direct contribution from the short posterior ciliary arteries.