The effects of exercise training on fatigue and dyspnea in heart failure.
The effects of exercise training on fatigue and dyspnea in heart failure.
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运动训练对心力衰竭疲劳和呼吸困难的影响。
DOI：
10.1016/j.ejcnurse.2007.08.002
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Hertzog,Melody
中科院分区：
文献类型：
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作者：
Pozehl,Bunny;Duncan,Kathleen;Hertzog,Melody
背景：运动训练对心力衰竭（HF）患者的生理益处已被证实，但很少有人知道训练对疲劳和呼吸困难症状的影响。目的：本研究的目的是研究24周运动训练干预后HF疲劳和呼吸困难症状。方法：本试验研究是一项随机、两组重复测量设计。干预组中的15名受试者在标准心脏康复环境中每周完成3次有氧和阻力训练的组合。对照组6名受试者，在24周的干预期间被指示不开始任何正式的锻炼program.Results：受试者（19名男性和2名女性）的平均年龄为66.2 ± 10.2岁，平均射血分数（EF）为28.4 ± 7.4%。非参数弗里德曼等级方差分析显示，运动组随着时间的推移显着降低了感觉疲劳（Piper疲劳量表）（χ2= 6.49，p = 0.04），而对照组没有变化（χ2= 0.93，p = 0.63）。运动组的呼吸困难随时间无显著性降低（χ2= 4.16，p = 0.13），而对照组从基线到12周有所降低，但到24周增加到高于基线值（χ2= 0.18，p = 0.91）。结论：这些结果为运动训练对HF患者疲劳和呼吸困难症状的有益作用提供了支持。需要更大规模的研究来评估运动对症状的反应。
Background:Physiological benefits of exercise training for heart failure (HF) patients have been demonstrated, however little is known about the effects of training on the symptoms of fatigue and dyspnea.Aim:The purpose of this study was to examine HF symptoms of fatigue and dyspnea in response to a 24-week exercise training intervention.Methods:This pilot study was a randomized, two-group repeated measures design. Fifteen subjects in the intervention group completed a combination of aerobic and resistance training three times per week in a standard cardiac rehabilitation setting. The control group consisted of 6 subjects who were instructed not to begin any formal exercise program during the 24-week intervention.Results:Subjects (19 males and 2 females) had a mean age of 66.2 ± 10.2 years and mean ejection fraction (EF) of 28.4 ± 7.4%. Non-parametric Friedman Analysis of Variance by Ranks showed the exercise group significantly decreased sensory fatigue (Piper Fatigue Scale) over time (χ2= 6.49,p= .04) while the control group did not change (χ2= 0.93,p= .63). Dyspnea showed a non-significant decrease over time for the exercise group (χ2= 4.16,p= .13) while the control group showed a decrease from baseline to 12 weeks but an increase to above baseline values by week 24 (χ2= 0.18,p= .91).Conclusion:These results provide support for the beneficial effects of exercise training on symptoms of fatigue and dyspnea in HF patients. Larger studies to evaluate symptom response to exercise are needed.