pymzML v2.0: introducing a highly compressed and seekable gzip format
pymzML v2.0: introducing a highly compressed and seekable gzip format
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DOI:
10.1093/bioinformatics/bty046
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发表时间:
2018-07-15
期刊:
影响因子:
5.8
通讯作者:
Fufezan, C.
中科院分区:
文献类型:
--
作者:
Koesters, M.;Leufken, J.;Fufezan, C.
Motivation: In the new release of pymzML (v2.0), we have optimized the speed of this established tool for mass spectrometry data analysis to adapt to increasing amounts of data in mass spectrometry. Thus, we integrated faster libraries for numerical calculations, improved data retrieving algorithms and have optimized the source code. Importantly, to adapt to rapidly growing file sizes, we developed a generalizable compression scheme for very fast random access and applied this concept to mzML files to retrieve spectral data.Results: pymzML performs at par with established C programs when it comes to processing times. However, it offers the versatility of a scripting language, while adding unprecedented fast random access to compressed files. Additionally, we designed our compression scheme in such a general way that it can be applied to any field where fast random access to large data blocks in compressed files is desired.