Effects of alcohol on disinhibition towards alcohol-related cues
Effects of alcohol on disinhibition towards alcohol-related cues
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DOI：
10.1016/j.drugalcdep.2012.06.025
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发表时间：
2013-01-01
影响因子：
4.2
通讯作者：
Munafo, Marcus R.
中科院分区：
文献类型：
--
作者：
Adams, Sally;Ataya, Alia F.;Munafo, Marcus R.
背景资料：我们研究了（1）急性酒精对酒精相关线索抑制和中性线索抑制的影响，（2）饮酒状态对酒精相关线索抑制和中性线索抑制的影响，以及（3）酒精或饮酒状态对两种不同线索类型的任何影响的相似性方法：受试者在受试者间设计中接受0.0 g/kg、0.4 g/kg或0.6 g/kg的酒精。健康、重度和轻度社交酒精使用者（n = 96）完成了酒精转移任务的词汇和图片提示版本。参与者被指示通过按空格键对目标刺激做出反应，但忽略干扰刺激。采用混合模型方差分析方法，分析了被试间干扰物类型（酒精、中性）和干扰物阻滞（转移、非转移）对词汇委托错误的影响（F [1，90] = 43.25，p <0.01）。
Background: We investigated (1) the effects of acute alcohol on inhibition of alcohol-related versus neutral cues, (2) the effects of drinking status on inhibition of alcohol-related versus neutral cues, and (3) the similarity of any effects of alcohol or drinking status across two different cue types (lexical versus pictorial).Methods: Participants received 0.0 g/kg, 0.4 g/kg or 0.6 g/kg of alcohol in a between-subjects design. Healthy, heavy and light social alcohol users (n = 96) completed both lexical and pictorial cue versions of an alcohol-shifting task. Participants were instructed to respond to target stimuli by pressing the spacebar, but to ignore distracter stimuli. Errors towards distracter stimuli were analysed using a series of mixed-model ANOVAs, with between-subjects factors of challenge and drinking status and within-subjects factors of distracter type (alcohol, neutral) and block (shift, non-shift).Results: Lexical commission error data indicated a main effect of distracter (F [1,90] = 43.25, p