Rationale for the Use of Colloids in the Treatment of Shock and Hypovolemia
Rationale for the Use of Colloids in the Treatment of Shock and Hypovolemia
复制标题
使用胶体治疗休克和低血容量的基本原理
DOI：
10.1111/j.1399-6576.1985.tb02342.x
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发表时间：
1985
影响因子：
2.1
通讯作者：
H. Haljamäe
中科院分区：
文献类型：
--
作者：
H. Haljamäe
问题是，“在低血容量性休克条件下，胶体或晶体是首选的复苏方法？”在这篇评论中有详细介绍。这两种类型的流体制度的影响，对恢复循环血容量，间质性补液，微血管血流，细胞代谢恢复和全身并发症，如成人呼吸窘迫综合征（ARDS），弥散性血管内凝血（DIC）和多器官功能衰竭的发病率被认为是。由于循环血容量的有效再膨胀和毛细血管血流的增强，含胶体的溶液似乎上级于晶体。复苏时间和由此的细胞缺氧损伤显著减少，同时防止过度组织水肿的形成。胶体似乎不会对肺功能产生不良影响。由于葡聚糖的抗血栓形成特性，葡聚糖在初始休克治疗中比其他类型的胶体具有相当大的优势，从而防止细胞聚集性，并令人信服地降低全身并发症（微栓塞综合征）的发生率。
The question, “Are colloids or crystalloids to be preferred for resuscitation in hypovolemic shock conditions?” is detailed in this review. The effects of these two types of fluid regimes on restitution of circulating blood volume, interstitial rehydration, microvascular blood flow, cellular metabolic recovery and on the incidence of systemic complications such as adult respiratory distress syndrome (ARDS), disseminated intravascular coagulation (DIC) and multiple organ failure are considered. Colloid containing solutions seem superior to crystalloids due to efficient reexpansion of circulating blood volume and enhancement of capillary blood flow. Resuscitation times and thereby the cellular hypoxic insult are considerable reduced while at the same time the formation of excessive tissue oedema is prevented. Colloids do not seem to adversely affect pulmonary function. Dextran has considerable advantages over other types of colloids for the initial shock treatment due to its antithrombotic properties whereby cell aggregability is prevented and the incidence of systemic complications (microembolism syndromes) is convincingly reduced.