elastix: A Toolbox for Intensity-Based Medical Image Registration
elastix: A Toolbox for Intensity-Based Medical Image Registration
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DOI：
10.1109/tmi.2009.2035616
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发表时间：
2010-01-01
影响因子：
10.6
通讯作者：
Pluim, Josien P. W.
中科院分区：
文献类型：
--
作者：
Klein, Stefan;Staring, Marius;Pluim, Josien P. W.
医学图像配准是医学图像处理中的一项重要任务。它指的是对可能来自不同模式(例如，磁共振和计算机断层扫描)、不同时间点(例如，后续扫描)和/或不同对象(在人口研究的情况下)的数据集进行对准的过程。文献中描述了大量用于图像配准的方法。不幸的是，没有一种方法可以适用于所有应用程序。因此，我们开发了一种用于基于强度的医学图像配准的公开可用的计算机程序。该软件由一组常用算法组成，这些算法通常用于解决医学图像配准问题。弹性的模块化设计允许用户针对特定应用快速配置、测试和比较不同的注册方法。命令行界面通过脚本实现了对大量数据集的自动化处理。通过三个不同配准方法的独立成分的实例实验，说明了弹性曲线在比较不同配准方法中的应用。
Medical image registration is an important task in medical image processing. It refers to the process of aligning data sets, possibly from different modalities (e. g., magnetic resonance and computed tomography), different time points (e. g., follow-up scans), and/or different subjects (in case of population studies). A large number of methods for image registration are described in the literature. Unfortunately, there is not one method that works for all applications. We have therefore developed elastix, a publicly available computer program for intensity-based medical image registration. The software consists of a collection of algorithms that are commonly used to solve medical image registration problems. The modular design of elastix allows the user to quickly configure, test, and compare different registration methods for a specific application. The command-line interface enables automated processing of large numbers of data sets, by means of scripting. The usage of elastix for comparing different registration methods is illustrated with three example experiments, in which individual components of the registration method are varied.