Antennal-specific pheromone-degrading aldehyde oxidases from the moths Antheraea polyphemus and Bombyx mori.
Antennal-specific pheromone-degrading aldehyde oxidases from the moths Antheraea polyphemus and Bombyx mori.
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DOI：
10.1016/s0021-9258(17)45430-5
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发表时间：
1990-11
期刊：
影响因子：
--
通讯作者：
R. Rybczynski;R. Vogt;M. Lerner
中科院分区：
文献类型：
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作者：
R. Rybczynski;R. Vogt;M. Lerner
雌蛾产生混合的气味化学物质，称为信息素。这些精确的化学混合物既吸引雄性，又引起适当的交配行为。为了找到雌蛾，雄蛾必须迅速察觉环境信息素浓度的变化。因此，触角内信息素浓度的调节是重要的，触角是它们的主要嗅觉器官。我们描述了触角特异性醛氧化酶从蛾天蚕和家蚕，能够分解代谢长链，不饱和醛，如他们的醛信息素。这些可溶性酶与雄性和雌性触角独特地相关，并且分别具有175和130 kDa的分子量。助理Polyphemus醛氧化酶定位于含有信息素受体细胞树突的嗅觉感受器。这些相同的感受器含有以前描述的感受器特异性酯酶，其降解A的乙酸酯组分。波吕斐摩斯信息素我们建议，感觉信息素降解酶调节信息素的浓度在受体空间，因此发挥了动态的作用，这些动物的信息素介导的生殖行为。
Female moths produce blends of odorant chemicals, called pheromones. These precise chemical mixtures both attract males and elicit appropriate mating behaviors. To locate females, male moths must rapidly detect changes in environmental pheromone concentration. Therefore, the regulation of pheromone concentration within antennae, their chief organ of smell, is important. We describe antennal-specific aldehyde oxidases from the moths Antheraea polyphemus and Bombyx mori that are capable of catabolizing long chain, unsaturated aldehydes such as their aldehyde pheromones. These soluble enzymes are associated uniquely with male and female antennae and have molecular masses of 175 and 130 kDa, respectively. The A. polyphemus aldehyde oxidase has been localized to the olfactory sensilla which contain the pheromone receptor cell dendrites. These same sensilla contain a previously described sensilla-specific esterase that degrades the acetate ester component of A. polyphemus pheromone. We propose that sensillar pheromone-degrading enzymes modulate pheromone concentration in the receptor space and hence play a dynamic role in the pheromone-mediated reproductive behaviors of these animals.