Tear secretion and tear film function in insulin dependent diabetics

Tear secretion and tear film function in insulin dependent diabetics
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DOI:
10.1136/bjo.84.1.19
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发表时间:
2000-01-01
影响因子:
4.1
通讯作者:
Goebbels, M
Goebbels, M
中科院分区:
医学2区
文献类型:
--
作者:
Goebbels, M

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背景-糖尿病患者经常主诉干眼症状,如烧灼感和/或异物感。本研究的目的是探讨糖尿病是否与泪膜功能障碍和/或泪液分泌不足有关。(年龄和性别匹配)我们进行泪液分泌的荧光光度测定,Schirmer试验,结果与健康对照组相比,糖尿病患者的泪液分泌试验读数降低(-37%,p
Background-Diabetic patients often complain of dry eye symptoms, such as burning and/or foreign body sensation. The aim of the present study was to investigate whether diabetes mellitus is correlated with tear film dysfunction and/or tear hyposecretion.Methods-In 86 consecutive insulin dependent diabetics with retinopathy and 84 non-diabetic controls (age and sex matched) we performed fluorophotometry of tear secretion, the Schirmer test, and impression cytology of the conjunctival epithelium and determined the tear film break up time.Results-When compared with the healthy control group diabetics showed decreased Schirmer test readings (-37%, p