Applications of Evolutionary Computing
Applications of Evolutionary Computing
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DOI:
10.1007/b96500
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发表时间:
2004
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影响因子:
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通讯作者:
G. Raidl;S. Cagnoni;J. Branke;D. Corne;R. Drechsler;Yaochu Jin;Colin G. Johnson;Penousal Machado;E. Marchiori;Franz Rothlauf;George D. Smith;Giovanni Squillero
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文献类型:
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作者:
G. Raidl;S. Cagnoni;J. Branke;D. Corne;R. Drechsler;Yaochu Jin;Colin G. Johnson;Penousal Machado;E. Marchiori;Franz Rothlauf;George D. Smith;Giovanni Squillero
This paper presents a memetic algorithm with self-adaptive local search, applied to protein structure prediction in an HP, cubic-lattice model. Besides describing in detail how the algorithm works, we report experimental results that justify important implementation choices, such as the introduction of speciation mechanisms and the extensive application of local search. Test runs on 48-mer chains show that the proposed algorithm has promising search capabilities.