Design and characterization of a low profile NaI(Tl) gamma camera for dedicated molecular breast tomosynthesis.

Design and characterization of a low profile NaI(Tl) gamma camera for dedicated molecular breast tomosynthesis.
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用于专用分子乳腺断层合成的低轮廓 NaI(Tl) 伽马相机的设计和表征。

DOI:
10.1117/12.2246561
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发表时间:
2016
期刊:
Proceedings of SPIE--the International Society for Optical Engineering
影响因子:
--
通讯作者:
Williams,MarkB
Williams,MarkB
中科院分区:
--
文献类型:
--
作者:
Polemi,AndrewM;Niestroy,Justin;Stolin,Alexander;Jaliparthi,Gangadhar;Wojcik,Randy;Majewski,Stan;Williams,MarkB

文献摘要

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正在开发一种新的低剖面伽马相机,用于双模态(X射线传输和伽马射线发射)断层合成系统。与系统当前的伽马照相机相比,新照相机具有更大的视场(~ 20 x25 cm),以更好地匹配系统的X射线探测器(~ 23 x29 cm),并且更薄(7.3 cm而不是10.3 cm),使照相机更容易定位在乳房顶面附近。它包含一个晶体间距为2.2 mm的像素化NaI(Tl)阵列,该阵列与Hamamatsu H8500 C位置敏感光电倍增管(PSPMT)的4x 5阵列光耦合。将供应商提供的每个PSPMT的连接器板替换为定制设计的板,a)将H8500 C的8x8电极阳极的64通道读数减少到16通道(8X和8 Y),B)执行增益非均匀性校正,以及c)减小PSPMT-基座组件的高度,每个模块的X和Y输出连接在一个网格框架中,在该网格的两个边缘,X和Y输出(32 Y × 40 X)耦合到放大器/输出板,其信号通过屏蔽带状电缆馈送到外部ADC。相机采用平行孔准直。我们描述了测量的相机成像性能,包括内在和外在的空间分辨率,检测灵敏度,响应的均匀性,能量分辨率为140 keV的伽马射线,和几何线性。
A new low profile gamma camera is being developed for use in a dual modality (x-ray transmission and gamma-ray emission) tomosynthesis system. Compared to the system’s current gamma camera, the new camera has a larger field of view (~20x25 cm) to better match the system’s x-ray detector (~23x29 cm), and is thinner (7.3 cm instead of 10.3 cm) permitting easier camera positioning near the top surface of the breast. It contains a pixelated NaI(Tl) array with a crystal pitch of 2.2 mm, which is optically coupled to a 4x5 array of Hamamatsu H8500C position sensitive photomultiplier tubes (PSPMTs). The manufacturer-provided connector board of each PSPMT was replaced with a custom designed board that a) reduces the 64 channel readout of the 8x8 electrode anode of the H8500C to 16 channels (8X and 8Y), b) performs gain non-uniformity correction, and c) reduces the height of the PSPMT-base assembly, 37.7 mm to 27.87 mm. The X and Y outputs of each module are connected in a lattice framework, and at two edges of this lattice, the X and Y outputs (32Y by 40X) are coupled to an amplifier/output board whose signals are fed via shielded ribbon cables to external ADCs. The camera uses parallel hole collimation. We describe the measured camera imaging performance, including intrinsic and extrinsic spatial resolution, detection sensitivity, uniformity of response, energy resolution for 140 keV gamma rays, and geometric linearity.