Physical activity and cause-specific mortality in men: Further evidence from the Whitehall study
Physical activity and cause-specific mortality in men: Further evidence from the Whitehall study
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DOI：
10.1023/a:1015609909969
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发表时间：
2001-01-01
影响因子：
13.6
通讯作者：
Smith, GD
中科院分区：
文献类型：
--
作者：
Batty, GD;Shipley, MJ;Smith, GD
有关体育活动与中风和癌症亚型的研究报告显示了不一致的结果。由于事件数量少，统计能力低，并且未能调整潜在的混杂变量，因此有些方法受到阻碍。本研究的目的是在一项前瞻性队列研究中，将身体活动与12个死亡率终点联系起来，该研究纳入了11,663名年龄在40-64岁之间的男性，他们在1967年至1969年进行的基线体检期间回答了有关旅行活动的询问。在25年的随访中，有4672人死亡。旅行活动与全因死亡率、冠心病、呼吸系统疾病和肺癌呈负相关，而与中风呈正相关。有证据表明，在调整潜在的混淆变量后，这些关联中的一些会减弱。我们对体力活动的简单衡量可能在一定程度上解释了所见的微弱关联。
Reports of studies relating physical activity to stroke and cancer sub-types indicate inconsistent findings. Some are hampered by low statistical power, owing to a low number of events, and a failure to adjust for potential confounding variables. The purpose of this study was to relate physical activity to 12 mortality endpoints in a prospective cohort study of 11,663 men aged 40-64 years who responded to an enquiry about travel activity during a baseline medical examination conducted between 1967 and 1969. During 25 years of follow-up there were 4672 deaths. Travel activity was inversely related to mortality attributable to all-causes, coronary heart disease, respiratory disease and lung cancer, whereas the association with stroke was positive. There was evidence for attenuation of some of these associations on adjustment for potentially confounding variables. Our simplistic measure of physical activity may, in part, explain the weak associations seen.