MPBLAST:: improved BLAST performance with multiplexed queries
MPBLAST:: improved BLAST performance with multiplexed queries
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DOI：
10.1093/bioinformatics/16.11.1052
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发表时间：
2000-11-01
期刊：
影响因子：
5.8
通讯作者：
Gish, W
中科院分区：
文献类型：
--
作者：
Korf, I;Gish, W
我们已经开发了一个程序，MPBLAST，增加了批量BLACKS搜索的吞吐量的多路复用（串联）查询序列，从而减少了实际数据库搜索的数量。观察到发射量与组分序列长度成反比增加。对于500 bp的测序读段大小的查询，看到了数量级的加速。
We have developed a program, MPBLAST that increases the throughput of batch BLASTN searches by multiplexing (concatenating) query sequences and thereby reducing the number of actual database searches performed. Throughput was observed to increase in reciprocal proportion to the component sequence length. For sequencing read-sized queries of 500 bp, an order of magnitude speed-up was seen.