Activities of tryptophan hydroxylase, [3,4-dihydroxyphenylalanine] decarboxylase, and monoamine oxidase as correlated with the appearance of monoamines in developing rat pineal gland
Activities of tryptophan hydroxylase, [3,4-dihydroxyphenylalanine] decarboxylase, and monoamine oxidase as correlated with the appearance of monoamines in developing rat pineal gland
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DOI：
10.1016/0024-3205(67)90107-5
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发表时间：
1967-01-01
期刊：
影响因子：
6.1
通讯作者：
OWMAN, C.
中科院分区：
文献类型：
--
作者：
HAKANSON, R.;LOMBARD des GOUTTES, M.-N.;OWMAN, C.
用荧光显微镜观察了发育期大鼠松果体单胺的出现。新生大鼠的松果体直到出生后1周才有明显的5-羟色胺[5-羟色胺]，3周龄时达到成年水平。松果体5-羟色胺同时存在于实质细胞和交感神经中。出生后第1周，松果体内神经中仅见去甲肾上腺素[去甲肾上腺素]。色氨酸羟基酶在出生时活性较高，而DOPA脱羧酶和单胺氧化酶在出生后很久才达到相应的活性水平。|摘要作者：来自auth。求和
The appearance of pineal monoamines in the developing rat was studied by fluorescence microscopy. The pineal gland of the newborn rat had no demonstrable 5-HT [5-hydroxytryptamine] until 1 week after birth; adult levels were reached at 3 weeks of age. Pineal 5-HT appeared simultaneously in parenchymal cells and sympathetic nerves. During the 1st week after birth only noradrenaline [nor-epinephrine] was found in the intrapineal nerves. High activity of tryptophan hydroxylase was registered at birth, whereas DOPA decarboxylase and monoamine oxidase attained a corresponding degree of activity much later. || ABSTRACT AUTHORS: From auth. sum