The metabolic syndrome among postmenopausal women in Ecuador
The metabolic syndrome among postmenopausal women in Ecuador
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DOI：
10.1080/09513590600890272
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发表时间：
2006-08-01
影响因子：
2
通讯作者：
Huc, Angelica
中科院分区：
文献类型：
--
作者：
Hidalgo, Luis A.;Chedraui, Peter A.;Huc, Angelica
背景资料。代谢综合征的患病率随着年龄的增长和绝经后的增加而增加，这可能在一定程度上解释了绝经后女性心血管疾病明显加速的原因。目标。目的了解厄瓜多尔绝经后妇女代谢综合征患病率及相关危险因素。在厄瓜多尔瓜亚基尔卡托利卡大学的生物医学研究所，40岁未使用激素治疗且子宫完整的绝经后妇女被要求参加代谢综合征筛查和教育项目。记录社会人口学数据、腰围和血压测量，并获取空腹血样用于血糖和血脂测定。根据结果对女性进行咨询和管理。代谢综合征的定义符合第三成人治疗小组的标准(ATP111)。325名绝经后妇女参加了这项计划。平均年龄(+/-标准差)为55.9+/-8.1岁，其中53.5%为54岁(中位数)。根据ATPIII标准，代谢综合征的患病率为41.5%。使用相同的标准，分别有38.8%、16.6%、56.9%和54.2%的女性出现高血压、糖尿病、高甘油三酯血症和腹型肥胖。在确诊患有高血压或糖尿病的女性中，超过40%的人对此一无所知。Logistic回归分析表明，年龄增加了高血压和糖尿病的风险(优势比(95%可信区间)分别为2.0(1.2-3.2)和1.6(0.9-3.0，p<；0.05)，这反过来又增加了高甘油三酯水平的风险。绝经后5年久坐的女性患腹型肥胖的风险更高，腹型肥胖与糖尿病和高血压有直接关系。在这一绝经后厄瓜多尔人口中，代谢综合征的患病率很高，其决定因素与年龄、绝经开始时间和久坐习惯有关。由于对心血管风险的影响，应该鼓励针对高危人群的咨询计划。
Background. The prevalence of the metabolic syndrome increases with age and after the onset of menopause, and may explain in part the apparent acceleration of cardiovascular disease in postmenopausal women. Objective. To determine the prevalence of metabolic syndrome and related risk determinants among postmenopausal women in Ecuador.Methods. Postmenopausal women >= 40 years of age, non-users of hormone therapy and with an intact uterus, were asked to participate in a metabolic syndrome screening and educational program at the Institute of Biomedicine of the Universidad Catolica of Guayaquil, Ecuador. Sociodemographic data, waist circumference and blood pressure measurements were recorded, and a fasting blood sample obtained for serum glucose and lipid profile determinations. Woman were counseled and managed according to the results. Metabolic syndrome was defined in accordance with the criteria of the Third Adult Treatment Panel (ATP 111).Results. Three hundred and twenty-five postmenopausal women entered the program. Mean (+/- standard deviation) age was 55.9 +/- 8.1 years, 53.5% of them were aged >= 54 years (median). The prevalence of metabolic syndrome, according to ATP III criteria, was 41.5%. Using the same criteria, 38.8%, 16.6%, 56.9% and 54.2% of the women presented with hypertension, diabetes, hypertriglyceridemia and abdominal obesity, respectively. More than 40% of women determined to have hypertension or diabetes lacked knowing so. Logistic regression analysis determined that age increased the risk of presenting hypertension and diabetes (odds ratio (95% confidence interval): 2.0 (1.2-3.2) and 1.6 (0.9-3.0), respectively, p < 0.05), entities which in turn duplicated the risk of having high triglyceride levels. Sedentary women with < 5 years since menopause onset were at higher risk of having abdominal obesity, which was directly related to diabetes and hypertension.Conclusions. In this postmenopausal Ecuadorian population the prevalence of the metabolic syndrome was high and its determinant factors related to age, time since menopause onset and sedentary habits. Because of the implications for cardiovascular risk, counseling programs directed toward high-risk populations should be encouraged.