Er:YAG laser in the treatment of periodontal sites with recurring chronic inflammation: a 12-month randomized, controlled clinical trial
Er:YAG laser in the treatment of periodontal sites with recurring chronic inflammation: a 12-month randomized, controlled clinical trial
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DOI：
10.1111/j.1600-051x.2012.01912.x
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发表时间：
2012-08-01
影响因子：
6.7
通讯作者：
Leknes, Knut N.
中科院分区：
文献类型：
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作者：
Krohn-Dale, Ivar;Boe, Olav E.;Leknes, Knut N.
目的：本随机对照临床试验的目的是比较使用掺铒钇铝石榴石（Er：YAG）激光进行囊袋清创术与传统清创术在维持治疗患者中的临床和微生物学效果。材料与方法15例患者，均为吸烟者，至少有4颗牙齿的剩余探诊深度（PD）=5 mm。两个颌骨象限中的两个囊袋被随机分配到使用Er：YAG激光（试验）或超声刮治器/刮匙（对照）进行龈下清创，每隔3个月进行一次。在基线、6个月和12个月时记录相对附着水平（RAL）、PD、探诊出血和牙菌斑。在相同的时间点采集龈下微生物样本，并使用棋盘DNA-DNA杂交技术进行分析。结果两组患者术后12个月的PD均较术前明显下降（p < 0.01）。在对照组中，12个月时平均初始PD从5.4 mm降至4.0 mm。在测试中，出现了类似的下降。在任何时间点均未显示显著的治疗间差异。平均RAL显示总体上没有显著的治疗间或治疗内差异（p > 0.05）。龈下微生物组成或总病原体无显著治疗间差异。结论Er：YAG激光治疗吸烟者复发性慢性炎症的疗效上级传统清创术。这似乎是第一次重复Er-YAG激光器械与机械器械在临床相关时间段内对复发性慢性炎症的牙周部位进行比较。
Aim The objective of this randomized, controlled clinical trial was to compare the clinical and microbiological effects of pocket debridement using erbium-doped: yttrium, aluminium and garnet (Er:YAG) laser with conventional debridement in maintenance patients. Material & Methods Fifteen patients, all smokers, having at least four teeth with residual probing depth (PD) =5 mm were recruited. Two pockets in two jaw quadrants were randomly assigned to subgingival debridement using an Er:YAG laser (test) or ultrasonic scaler/curette (control) at 3-month intervals. Relative attachment level (RAL), PD, bleeding on probing and dental plaque were recorded at baseline and at 6 and 12 months. Microbiological subgingival samples were taken at the same time points and analysed using a checkerboard DNA-DNA hybridization technique. Results A significant decrease in PD took place in both treatments from baseline to 12 months (p < 0.01). In the control, the mean initial PD decreased from 5.4 to 4.0 mm at 12 months. For the test, a similar decrease occurred. No significant between-treatment differences were shown at any time point. The mean RAL showed no overall significant inter- or intra-treatment differences (p > 0.05). No significant between-treatment differences were observed in subgingival microbiological composition or total pathogens. Conclusion The results failed to support that an Er:YAG laser may be superior to conventional debridement in the treatment of smokers with recurring chronic inflammation. This appears to be the first time that repeated Er-YAG laser instrumentation has been compared with mechanical instrumentation of periodontal sites with recurring chronic inflammation over a clinically relevant time period.