Frailty Predicts New and Persistent Depressive Symptoms Among Community-Dwelling Older Adults: Findings From Singapore Longitudinal Aging Study
Frailty Predicts New and Persistent Depressive Symptoms Among Community-Dwelling Older Adults: Findings From Singapore Longitudinal Aging Study
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DOI：
10.1016/j.jamda.2013.10.001
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发表时间：
2014-01-01
影响因子：
7.6
通讯作者：
Ng, Tze Pin
中科院分区：
文献类型：
--
作者：
Feng, Liang;Nyunt, Ma Shwe Zin;Ng, Tze Pin
目的：本研究的目的是检查基线时身体虚弱与基线和随访时抑郁症状之间的横向和纵向关系。设计：四年前瞻性研究。设置：新加坡东南地区的社区。参与者：我们分析了新加坡纵向老化研究-I中1827名55岁及以上的中国老年人的数据。测量：脆弱表型（基于Fried标准）在基线时确定，抑郁症状（老年抑郁量表>= 5）在基线和随访在2年和4 years.Results：人口的平均年龄为65.9（标准差7.26）。基线时，11.4%（n = 209）有抑郁症状，32.4%（n = 591）为虚弱前期，2.5%（n = 46）为虚弱。在基线数据的横断面分析中，控制人口统计学、合并症和其他混杂因素的校正比值比（OR）和95%置信区间为：易虚弱组1.69（1.23-2.33），虚弱组2.36（1.08-5.15），（P线性趋势
Objective: This study aimed to examine the cross-sectional and longitudinal relationships between physical frailty at baseline and depressive symptoms at baseline and at follow-up.Design: Four-year prospective study.Setting: Communities in the South East Region of Singapore.Participants: We analyzed data of 1827 older Chinese adults aged 55 and above in the Singapore Longitudinal Aging Study-I.Measurements: The frailty phenotype (based on Fried criteria) was determined at baseline, depressive symptoms (Geriatric Depression Scale >= 5) at baseline and follow-ups at 2 and 4 years.Results: The mean age of the population was 65.9 (standard deviation 7.26). At baseline, 11.4% (n = 209) had depressive symptoms, 32.4% (n = 591) were prefrail and 2.5% (n = 46) were frail. In cross-sectional analysis of baseline data, the adjusted odds ratios (OR)s and 95% confidence intervals controlling for demographic, comorbidities, and other confounders were 1.69 (1.23-2.33) for prefrailty and 2.36 (1.08-5.15) for frailty, (P for linear trend