Architektur eines Heterochromatinkomplexes
Architektur eines Heterochromatinkomplexes
复制标题
异染色质复合体的结构
DOI:
10.1007/s12268-015-0618-3
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发表时间:
2015
期刊:
影响因子:
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通讯作者:
Ann Ehrenhofer-Murray
中科院分区:
文献类型:
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作者:
Ann Ehrenhofer-Murray
The regulation of gene expression in eukaryotes is achieved by differential chromatin packaging of the genome. Heterochromatin constitutes a repressive type of chromatin in which non-histone proteins bind to the chromatin fibre and restrict gene expression. The silent information regulator (SIR) complex fromSaccharomyces cerevisiaeserves as a model for eukaryotic heterochromatin. Here, our current structural knowledge of SIR-mediated chromatin is discussed.