Jones-matrix imaging of biological tissues with quadruple-channel optical coherence tomography
Jones-matrix imaging of biological tissues with quadruple-channel optical coherence tomography
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DOI：
10.1117/1.1483878
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发表时间：
2002-07-01
影响因子：
3.5
通讯作者：
Wang, LHV
中科院分区：
文献类型：
--
作者：
Jiao, SL;Wang, LHV
采用新型双光源双探测器偏振敏感光学相干层析成像技术（OCT）测量散射生物组织的二维深度分辨琼斯矩阵图像。利用该OCT系统，可以在单次扫描中确定琼斯矩阵。实验结果表明，该系统可以有效地应用于软组织的测量，这是不稳定的硬组织。偏振参数，如双衰减，双折射，和取向的快轴可以通过分解的测量琼斯矩阵提取。热处理猪肌腱的琼斯矩阵显示热损伤的双折射减少。猪皮肤和牛软骨的Jones矩阵还显示，猪皮肤和牛软骨中的胶原纤维的密度和取向不像猪肌腱中那样均匀分布。生物电测量对组织的变化很敏感，因为它是基于相位对比的。(C)2002年，美国光电仪器工程师学会。
Two-dimensional depth-resolved Jones-matrix images of scattering biological tissues were measured with novel double-source double-detector polarization-sensitive optical coherence tomography (OCT). The Jones matrix can be determined in a single scan with this OCT system. The experimental results show that this system can be effectively applied to the measurement of soft tissues, which are less stable than hard tissues. Polarization parameters such as diattenuation, birefringence, and orientation of the fast axis can be extracted through decomposition of the measured Jones matrix. The Jones matrix of thermally treated porcine tendon showed a reduction of birefringence from thermal damage. The Jones matrices of porcine skin and bovine cartilage also revealed that the density and orientation of the collagen fibers in porcine skin and bovine cartilage are not distributed as uniformly as in porcine tendon. Birefringence is sensitive to changes in tissue because it is based on phase contrast. (C) 2002 Society of Photo-Optical Instrumentation Engineers.