Self-Assembled Monolayer-Based Electrodes for Selective Determination of Cu^2+ and Ag^+ Ions with Antifouling Activity against Protein Adsorption
Self-Assembled Monolayer-Based Electrodes for Selective Determination of Cu^2+ and Ag^+ Ions with Antifouling Activity against Protein Adsorption
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用于选择性测定 Cu^2 和 Ag^ 离子的自组装单层电极，具有针对蛋白质吸附的防污活性
DOI：
10.2116/analsci.15.857
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发表时间：
1999
期刊：
影响因子：
--
通讯作者：
K. Ogura
中科院分区：
文献类型：
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作者：
T. Nagaoka;Zhidong Chen;H. Okuno;M. Nakayama;K. Ogura
研究了3，3 ′-硫代二丙酸和正癸基丙酸在金电极上形成的自组装膜对Cu ^2+和Ag^+的灵敏和选择性测定。研究发现，即使在蛋白质存在的情况下，单层也能提供上级的灵敏度和稳定性。对溶液pH值和浓缩时间等因素进行了优化，使线性扫描阳极溶出伏安法在信噪比为2时对Cu^2+和Ag^+的检测限分别达到2×10^-9 M和6×10^-8 M。在白蛋白的存在下，修饰电极的电流，为裸电极的1.75倍，显示出比以前报道的纤维素涂层电极（1.13倍）的显着性能改善。使用该电极的主要优点之一是对蛋白质吸附具有优异的吸附活性，并具有高度选择性的金属离子抑制/浓缩能力，这可以在不使用汞膜进行预浓缩的情况下实现。
Self-assembled monolayers consisting of 3,3′-thiodipropionic acid and n -decyl mercaptan formed on gold electrodes have been studied for sensitive and selective determination of Cu^2+ and Ag^+ ions. The monolayers were found to provide both superior sensitivities and stabilities even in the presence of protein. Various factors, such as solution pH and concentration time, were optimized to obtain detection limits of 2×10^–9 M and 6×10^–8 M for Cu^2+ and Ag^+ ions at an S/N ratio of 2 by linear-sweep anodic stripping voltammetry. In the presence of albumin, the currents of the modified electrode, 1.75 times as great as those for the bare electrode, show a significant performance improvement over the previously reported cellulose coated electrode (1.13 times). One of the main advantages of using this electrode is an excellent antifouling activity against protein adsorption, coupled with highly selective metal-ion suppression/concentration capabilities, which can be attained without using a mercury film for preconcentration.