[Air pollution and cardiovascular and cerebrovascular disease: Epidemiologic data].
[Air pollution and cardiovascular and cerebrovascular disease: Epidemiologic data].
复制标题
空气污染与心脑血管疾病：流行病学资料[J].
作者：
M. Zeller;M. Giroud;Clotilde Royer;I. Benatru;J. Besancenot;L. Rochette;Y. Cottin
最近的数据表明，空气污染影响急性动脉粥样硬化血栓事件的风险，包括心肌梗死和缺血性中风。20世纪90年代开始的主要流行病学研究首先检查了大气污染对呼吸系统的影响，然后重点关注污染高峰如何影响心血管风险。这些研究使用了来自北美和亚洲大城市以及几个欧洲大城市的数据，以证明空气污染与心脑血管死亡率之间存在明显的关系。他们还观察到，在空气污染严重的日子里，因心肌梗死和脑血管事故住院的人数有所增加。所涉及的污染物尚未明确指定，但似乎细悬浮颗粒物（PM2.5）和臭氧等气态污染物似乎对这些有害影响起了很大作用。对这些数据的全面分析表明，有必要对与空气污染有关的心脑血管风险进行全面评估，特别是在法国大都市地区。精确识别受特定污染物影响的高风险人群，对于提高预防战略的针对性至关重要。
Recent convergent data suggest that air pollution affects the risk of acute atherothrombotic events including both myocardial infarction and ischemic stroke. The principal epidemiologic studies begun in the 1990s first examined the respiratory effects of atmospheric pollution and then focused on how pollution peaks affected cardiovascular risk. These studies used data from large metropolitan areas in North America and Asia as well as several large European cities to demonstrate the clear existence of a relation between air pollution and cardio- and cerebrovascular mortality. They also observed an increase in hospital admissions for myocardial infarctions and cerebrovascular accidents on days with high air pollution levels. The pollutants involved have not yet been clearly designated, but it appears that fine suspended particulate matter (PM2.5) and gaseous pollutants such as ozone appear to contribute strongly to these harmful effects. A complete analysis of these data shows the need for a thorough evaluation of the cardio- and cerebrovascular risks associated with air pollution, especially in French metropolitan areas. Precise identification of those at high risk from specific pollutants is essential to improve targeting of prevention strategies.