Sitting time and health outcomes among Mexican origin adults: obesity as a mediator.
Sitting time and health outcomes among Mexican origin adults: obesity as a mediator.
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DOI：
10.1186/1471-2458-12-896
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发表时间：
2012-10-23
影响因子：
4.5
通讯作者：
Koehly LM
中科院分区：
文献类型：
--
作者：
de Heer HD;Wilkinson AV;Strong LL;Bondy ML;Koehly LM
在非西班牙裔白色人群中，坐着的时间和久坐不动的行为与不良健康结果相关，包括肥胖、糖尿病和心血管疾病（CVD）。尽管西班牙裔人群的心血管疾病风险较高，但在西班牙裔人群中尚未描述类似的相关性。本研究旨在评估一个大型墨西哥裔成年人队列（N= 11，268）中坐着时间与肥胖、自我报告诊断的糖尿病、高血压和高胆固醇之间的关联，并评估肥胖是否介导了这些关联。采用横断面设计，在2010年底分析了2004年至2010年期间收集的数据。回归分析评估了自我报告的每日静坐时间与疾病结果之间的关联，控制了人口统计学，就业状况，家族疾病史以及轻，中度和剧烈的体力活动。参与者主要是女性（81.1%）墨西哥裔成年人。坐着的时间与肥胖、糖尿病和高血压的几率增加有关，但与高胆固醇无关。报告坐着> 4小时/天的参与者与坐着1-2小时/天的参与者相比，肥胖的校正比值比为OR=1.55（95% CI 1.39，1.73），p<.001，糖尿病OR=1.29（95% CI，1.09，1.52），p=.003，高血压OR=1.17（95% CI，1.01，1.37），p=.041。受身体活动和就业状况控制的协会。对高血压和糖尿病的影响是由肥胖介导的。坐着的时间与有害的健康结果显著相关，与体力活动无关。肥胖介导了糖尿病和高血压的这些关系。未来的研究应评估是否干预解决坐的时间是可行的和有效的墨西哥裔人口。
Sitting time and sedentary behaviors have been associated with adverse health outcomes including obesity, diabetes and cardiovascular disease (CVD) within non- Hispanic White populations. Similar associations have not been described within Hispanic populations despite their high CVD risk profile. This study aimed to assess the association between sitting time and obesity, self-reported diagnosed diabetes, hypertension and high cholesterol among a large cohort (N=11,268) of Mexican origin adults and to assess whether obesity mediated these associations. Using a cross-sectional design, data collected between 2004 and 2010 were analyzed in late 2010. Regression analyses evaluated associations between self-reported daily sitting hours and disease outcomes, controlling for demographics, employment status, family disease history, and light, moderate and strenuous physical activity. Participants were mostly female (81.1%) Mexican origin adults. Sitting time was associated with increased odds of being obese, having diabetes and having hypertension, but not high cholesterol. Adjusted odds ratios of participants who reported sitting > 4 hours/day compared to those sitting 1-2 hours/day were for obesity OR=1.55 (95% CI 1.39, 1.73), p<.001, for diabetes OR=1.29 (95% CI, 1.09, 1.52), p=.003, for hypertension OR=1.17 (95% CI, 1.01, 1.37), p=.041. Associations controlled for physical activity and employment status. Effects on hypertension and diabetes were mediated by obesity. Sitting time was significantly associated with detrimental health outcomes, independent of physical activity. Obesity mediated these relationships for diabetes and hypertension. Future research should assess whether interventions addressing sitting time are feasible and effective among Mexican origin populations.
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影响因子：
7.6
作者：
BARON, RM;KENNY, DA
通讯作者：
KENNY, DA
影响因子：
5
作者：
Matthews, Charles E.;Chen, Kong Y.;Troiano, Richard P.
通讯作者：
Troiano, Richard P.
影响因子：
7.7
作者：
Hamilton, Marc T.;Hamilton, Deborah G.;Zderic, Theodore W.
通讯作者：
Zderic, Theodore W.
DOI：
10.1038/oby.2005.173
发表时间：
2005-08-01
期刊：
OBESITY RESEARCH
影响因子：
--
作者：
Brown, WJ;Williams, L;Dobson, AJ
通讯作者：
Dobson, AJ
影响因子：
16.2
作者：
Gao, Xiang;Nelson, Miriam E.;Tucker, Katherine L.
通讯作者：
Tucker, Katherine L.