Brain Midline Shift Measurement and Its Automation: A Review of Techniques and Algorithms.
Brain Midline Shift Measurement and Its Automation: A Review of Techniques and Algorithms.
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DOI：
10.1155/2018/4303161
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发表时间：
2018
影响因子：
7.6
通讯作者：
Xiao F
中科院分区：
文献类型：
--
作者：
Liao CC;Chen YF;Xiao F
脑中线移位（MLS）是一个重要的特征，可以通过各种成像方式测量，包括x射线、超声、计算机断层扫描和磁共振成像。颅内中线结构的移位有助于颅内病变的诊断，尤其是外伤性脑损伤、脑卒中、脑肿瘤和脓肿。作为颅内压升高的标志，MLS也是颅内肿块或肿块效应引起的脑灌注减少的指标。我们回顾了使用MLS预测颅内肿块患者预后的研究。在一些研究中，MLS也与临床特征相关。自动化MLS测量算法在协助人类专家评估脑图像方面具有重要的潜力。在基于对称的算法中，检测变形的中线，并将其与理想中线的距离作为最大线距。在以地标为基础的研究中，MLS是在确定特定解剖地标后测量的。为了验证这些算法，使用这些算法的测量结果与人类专家进行的MLS测量结果进行了比较。除了在给定的影像学研究中测量MLS外，MLS还有一些新的应用，包括比较治疗前后的多个MLS测量，以及开发其他特征来指示质量效应。最后对今后的研究提出了建议。
Midline shift (MLS) of the brain is an important feature that can be measured using various imaging modalities including X-ray, ultrasound, computed tomography, and magnetic resonance imaging. Shift of midline intracranial structures helps diagnosing intracranial lesions, especially traumatic brain injury, stroke, brain tumor, and abscess. Being a sign of increased intracranial pressure, MLS is also an indicator of reduced brain perfusion caused by an intracranial mass or mass effect. We review studies that used the MLS to predict outcomes of patients with intracranial mass. In some studies, the MLS was also correlated to clinical features. Automated MLS measurement algorithms have significant potentials for assisting human experts in evaluating brain images. In symmetry-based algorithms, the deformed midline is detected and its distance from the ideal midline taken as the MLS. In landmark-based ones, MLS was measured following identification of specific anatomical landmarks. To validate these algorithms, measurements using these algorithms were compared to MLS measurements made by human experts. In addition to measuring the MLS on a given imaging study, there were newer applications of MLS that included comparing multiple MLS measurement before and after treatment and developing additional features to indicate mass effect. Suggestions for future research are provided.