Sleep enhances exposure therapy

Sleep enhances exposure therapy
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DOI:
10.1017/s0033291713001748
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发表时间:
2014-05-01
影响因子:
6.9
通讯作者:
Rasch, B.
Rasch, B.
中科院分区:
医学1区
文献类型:
--
作者:
Kleim, B.;Wilhelm, F. H.;Rasch, B.

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研究背景睡眠有助于记忆巩固。在这里,我们测试了暴露心理治疗后睡眠对记忆巩固的有益作用。方法根据DSM-IV,共有40名患有蜘蛛恐惧症的个体接受了一次虚拟现实暴露治疗,并在90 min内睡觉或保持清醒。结果与清醒相比,暴露治疗后的睡眠导致自我报告的恐惧更好地减少(p=0.045,d=0.47)和灾难性的蜘蛛相关的认知(p=0.026,d=0.53)在接近活蜘蛛,都在1周后测试。这两个减少与更大的百分比阶段2 sleep.ConclusionsOur结果表明,睡眠成功的心理治疗,如暴露疗法,提高了治疗效果,可能是通过加强新的非恐惧的记忆痕迹治疗过程中建立。这些发现提供了一个重要的非侵入性替代最近试图促进治疗记忆消退和巩固过程与药理学或行为干预。
BackgroundSleep benefits memory consolidation. Here, we tested the beneficial effect of sleep on memory consolidation following exposure psychotherapy of phobic anxiety.MethodA total of 40 individuals afflicted with spider phobia according to DSM-IV underwent a one-session virtual reality exposure treatment and either slept for 90min or stayed awake afterwards.ResultsSleep following exposure therapy compared with wakefulness led to better reductions in self-reported fear (p=0.045, d=0.47) and catastrophic spider-related cognitions (p=0.026, d=0.53) during approaching a live spider, both tested after 1 week. Both reductions were associated with greater percentages of stage 2 sleep.ConclusionsOur results indicate that sleep following successful psychotherapy, such as exposure therapy, improves therapeutic effectiveness, possibly by strengthening new non-fearful memory traces established during therapy. These findings offer an important non-invasive alternative to recent attempts to facilitate therapeutic memory extinction and consolidation processes with pharmacological or behavioral interventions.