Occurrence of and temporal trends in fidgety general movements in infants born extremely preterm/extremely low birthweight and term-born controls
Occurrence of and temporal trends in fidgety general movements in infants born extremely preterm/extremely low birthweight and term-born controls
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DOI：
10.1016/j.earlhumdev.2019.05.018
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发表时间：
2019-08-01
影响因子：
2.5
通讯作者：
Spittle, Alicia J.
中科院分区：
文献类型：
--
作者：
Kwong, Amanda K. L.;Olsen, Joy E.;Spittle, Alicia J.
Background: Fidgety general movements have high predictive validity for later cerebral palsy (CP) but their temporal organisation requires further understanding for assessment accuracy.Aims: To describe the occurrence of and temporal trends in fidgety movements, and whether they differ between infants born preterm and at term.Study design: Cohort study.Subjects: We assessed 155 EP/ELBW infants and 185 term-born infants born extremely preterm (EP; < 28 weeks' gestation) and/or extremely low birthweight (ELBW; < 1000 g birthweight) or at term (37-42 weeks' gestation) in the state of Victoria, Australia.Outcome measures: Parents of infants submitted up to two videos at 12-13(+6) and/or 14-16(+6) weeks' corrected age of infants' general movements. Videos were scored using the Prechtl General Movements Assessment (GMA) (fidgety) and classified as normal or absent/abnormal. Infants with at least one normal GMA were classified as normal. Individual GMA trajectories were analysed over time using logistic regression.Results: Overall, infants born EP/ELBW were more likely to have absent/abnormal fidgety movements than term-born infants (23% versus 3%, odds ratio [OR] 8.50 (95% confidence interval (CI) 3.48-20.8, p < 0.001). Fewer EP/ELBW and term-born infants showed absent/abnormal fidgety movements with each week of increasing age (EP/ELBW OR 0.46, 95% CI 0.25-0.84, p = 0.01; term-born OR 0.35, 95% CI 0.16-0.8, p = 0.01; interaction, p = 0.53).Conclusions: Absent/abnormal fidgety movements are more prevalent in infants born EP/ELBW than at term. Fidgety movements normalise with older age in both infants born EP/ELBW and at term between 12 and 16(+6) weeks' corrected age.
