Arterial plasma potassium measured continuously during exercise in man.
Arterial plasma potassium measured continuously during exercise in man.
复制标题
在人体运动过程中连续测量动脉血浆钾。
作者：
R. Linton;M. Lim;C. Wolff;P. Wilmshurst;D. M. Band
3名正常受试者在短时间（5-7 min）运动（100w）时获得5个连续的动脉血浆钾记录。在这些受试者中，每隔0.5-1.0分钟抽取肝静脉血，并在体外分析血浆钾。动脉血浆钾在运动开始时迅速上升，从3.8 +/- 0.3 mmol/l（平均+/- SD）上升到5.4 +/- 0.1 mmol/l的平台水平。对上述1名受试者和另1名受试者进行普萘洛尔阻断后的研究。这导致运动期间动脉血浆钾的急剧上升。肝静脉钾测量表明，在运动过程中，肝脏可能对钾的变化影响不大。运动时动脉血浆钾的变化迅速而显著。如果传递到细胞外液，这些变化将改变细胞的跨膜电位，从而可能改变受体的敏感性。
Five continuous records of arterial plasma potassium were obtained from three normal subjects during brief periods (5-7 min) of exercise (100 W). In two of these subjects hepatic venous blood samples were withdrawn at 0.5-1.0 min intervals and analysed in vitro for plasma potassium. Arterial plasma potassium rose rapidly at the start of exercise from 3.8 +/- 0.3 mmol/l (mean +/- SD) to plateau levels of 5.4 +/- 0.1 mmol/l. One of the above subjects and a further subject were studied after beta-blockade with propranolol. This resulted in an exaggerated rise in arterial plasma potassium during exercise. Hepatic venous potassium measurements indicated that the liver probably had little effect on potassium changes during exercise. The changes in arterial plasma potassium during exercise are rapid and substantial. If transmitted to the extracellular fluid these changes would alter cell transmembrane potential and might as a result alter receptor sensitivity.