Prolonged QRS duration as a predictor of right ventricular dysfunction after balloon pulmonary angioplasty
Prolonged QRS duration as a predictor of right ventricular dysfunction after balloon pulmonary angioplasty
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DOI：
10.1016/j.ijcard.2018.11.026
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发表时间：
2019-04-01
影响因子：
3.5
通讯作者：
Yasuda, Satoshi
中科院分区：
文献类型：
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作者：
Asano, Ryotaro;Ogo, Takeshi;Yasuda, Satoshi
背景：球囊肺血管成形术（BPA）已显示出对慢性血栓栓塞性肺动脉高压（CTEPH）的有益作用。然而，先前的研究表明BPA后心输出量改善较少，症状残留，意味着右心室（RV）功能恢复较差。因此，我们调查了残余的RV功能障碍后BPA揭示的危险因素，临床效果，和可能的潜在的组织病理学mechanism.Methods和结果：我们调查了61个连续CTEPH患者进行心血管磁共振前和3个月和12个月后BPA系列。RV残余功能障碍（RD）定义为RV舒张末期容积指数>100 ml/m2或RV射血分数（EF）
Background: Balloon pulmonary angioplasty (BPA) has shown beneficial effects for chronic thromboembolic pulmonary hypertension (CTEPH). However, previous studies have shown less cardiac output improvement and symptoms remaining after BPA, implying poor right ventricular (RV) function recovery. Therefore, we investigated the residual RV dysfunction after BPA to reveal risk factors, clinical effects, and possible underlying histopathological mechanisms.Methods and results: We investigated 61 consecutive CTEPH patients who underwent cardiovascular magnetic resonance before and 3 and 12 months after BPA series. Residual dysfunction (RD) of RV was defined as RV end-diastolic volume index >100 ml/m(2) or RV ejection fraction (EF)