Pyronepolyene C-glucosides with NF-κB inhibitory and anti-influenza A viral (H1N1) activities from the sponge-associated fungus Epicoccum sp JJY40

Pyronepolyene C-glucosides with NF-κB inhibitory and anti-influenza A viral (H1N1) activities from the sponge-associated fungus Epicoccum sp JJY40
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DOI:
10.1016/j.bmcl.2012.03.044
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发表时间:
2012-05-01
影响因子:
2.7
通讯作者:
Li, Dehai
Li, Dehai
中科院分区:
医学4区
文献类型:
--
作者:
Peng, Jixing;Jiao, Jieying;Li, Dehai

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从海绵伴生真菌Epicoccum sp.中分离得到一个新的吡喃多烯C-葡萄糖苷,命名为iso-D8646-2-6(1)和已知的相关化合物D8646-2-6(2)。JJY40。它们具有抑制核因子-kappa B和抗甲型H1N1流感病毒的活性。(C)2012爱思唯尔有限公司。保留所有权利。
A new pyronepolyene C-glucoside, named iso-D8646-2-6 (1) together with the known related compound D8646-2-6 (2), was isolated from the sponge-associated fungus Epicoccum sp. JJY40. They showed NF-kappa B inhibitory and anti-influenza A viral (H1N1) activities. (C) 2012 Elsevier Ltd. All rights reserved.