Influence of Geometry of Transplanted Tooth and Bone on Transformation of Fibroblasts 1
Influence of Geometry of Transplanted Tooth and Bone on Transformation of Fibroblasts 1
复制标题
移植牙齿和骨骼的几何形状对成纤维细胞转化的影响1
DOI：
10.3181/00379727-143-37381
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发表时间：
1973
影响因子：
--
通讯作者：
C. Huggins
中科院分区：
文献类型：
--
作者：
A. Reddi;C. Huggins
Summary Allogeneic transplants of demineralized powdered bone or whole teeth in different shapes transformed fibroblasts to cartilage and bone. Coarse powders of bone elicited significantly higher yields of transformation products than fine powder did; criteria of transformation included histologic findings, alkaline phosphatase activity, 35S and 32P incorporation. The temporal sequence of fibro-blast-chondroblast-osteoblast transformation was profoundly influenced by the geometry of the transformant. The incursion of capillaries among the transformed cells resulted in chondrolysis.
