EBV and MS: The evidence is growing stronger.

EBV and MS: The evidence is growing stronger.
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EBV 和 MS:证据越来越充分。

DOI:
10.1016/j.cell.2023.11.023
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发表时间:
2023
期刊:
影响因子:
64.5
通讯作者:
Farrell PJ
Farrell PJ
中科院分区:
生物学1区
文献类型:
--
作者:
Farrell PJ

文献摘要

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EB病毒(EBV)特异性抗体的自身免疫交叉反应与多发性硬化(MS)的发生有关。在这一期的细胞,Vietzen等人。确定其他免疫调节机制,保护健康人免受自身免疫,但在MS病例中减少。结果证实了EBV和MS之间的联系。
Autoimmune cross-reaction of specific antibodies to Epstein-Barr virus (EBV) has been associated with development of multiple sclerosis (MS). In this issue ofCell, Vietzen et al. identify additional immunological regulatory mechanisms that protect against autoimmunity in healthy people but are reduced in MS cases. The results confirm the link between EBV and MS.