Effects of altitude versus economic status on birth weight and body shape at birth
Effects of altitude versus economic status on birth weight and body shape at birth
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DOI：
10.1203/00006450-200104000-00009
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发表时间：
2001-04-01
影响因子：
3.6
通讯作者：
Barker, DJP
中科院分区：
文献类型：
--
作者：
Giussani, DA;Phillips, PS;Barker, DJP
令人信服的证据表明，出生时的小尺寸与后来的心血管疾病有关，这重新引起并扩大了对胎儿生长决定因素的临床和科学兴趣。虽然母体营养对胎儿生长的影响已被广泛研究，但对母胎缺氧的影响知之甚少。本研究通过调查玻利维亚高海拔与经济状况对出生体重和出生时体型的影响，验证了在高原地区，高海拔而不是母亲的经济状况与胎儿生长减少和改变有关的假设。玻利维亚在地理和社会经济方面都是独一无二的。它包括几个高地（海拔3500米以上）和低地（
The compelling evidence linking small size at birth with later cardiovascular disease has renewed and amplified a clinical and scientific interest in the determinants of fetal growth. Although the effects of maternal nutrition on fetal growth have been extensively studied, comparatively little is known about the effects of maternofetal hypoxia. This study tested the hypothesis that in highland regions, high altitude rather than maternal economic status is associated with reduced and altered fetal growth by investigating the effects of high altitude versus economic status on birth weight and body shape at birth in Bolivia. Bolivia is geographically and socioeconomically unique. It contains several highland (>3500 m above sea level) and lowland (