Ethics of clinical trials from a Bayesian and decision analytic perspective: whose equipoise is it anyway?

Ethics of clinical trials from a Bayesian and decision analytic perspective: whose equipoise is it anyway?
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DOI:
10.1136/bmj.326.7396.980
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发表时间:
2003-05-03
影响因子:
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通讯作者:
Lilford, RJ
Lilford, RJ
中科院分区:
医学1区
文献类型:
--
作者:
Lilford, RJ

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病人的平衡,还是医生的平衡,决定病人是否进入临床试验?要求病人同意试验的人是在掩盖伦理上的复杂性。选择应该基于事件的概率(专家可能知道)和患者对这些事件的价值(只有患者才能知道)。
Should the equipoise of the patient, or that of the doctor, determine whether a patient enters a clinical trial? People asking patients to consent to trials are glossing over the ethical complexities. Choices should be based both on probabilities of events (which experts might know) and on the value that a patient places on those events (which only the patient can know).