Percutaneous Transluminal Pulmonary Angioplasty for the Treatment of Chronic Thromboembolic Pulmonary Hypertension
Percutaneous Transluminal Pulmonary Angioplasty for the Treatment of Chronic Thromboembolic Pulmonary Hypertension
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DOI：
10.1161/circinterventions.112.971390
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发表时间：
2012-12-01
影响因子：
5.6
通讯作者：
Satoh, Toru
中科院分区：
文献类型：
--
作者：
Kataoka, Masaharu;Inami, Takumi;Satoh, Toru
慢性血栓栓塞性肺动脉高压导致肺动脉高压和右心衰竭。本研究的目的是探讨经皮腔内肺动脉成形术（PTPA）治疗慢性血栓栓塞性肺动脉高压的疗效。方法和结果29例慢性血栓栓塞性肺动脉高压患者接受PTPA。1例患者发生了PTPA并发症--导丝穿孔，并在术后2天死亡。在其余28例患者中，PTPA在手术时没有立即改善血流动力学。然而，在随访（6.0+/-6.9个月）后，纽约心脏协会功能分级和血浆B型利钠肽水平显著改善（均P
Background-Chronic thromboembolic pulmonary hypertension leads to pulmonary hypertension and right-sided heart failure. The purpose of this study was to investigate the efficacy of percutaneous transluminal pulmonary angioplasty (PTPA) for the treatment of chronic thromboembolic pulmonary hypertension.Methods and Results-Twenty-nine patients with chronic thromboembolic pulmonary hypertension underwent PTPA. One patient had a wiring perforation as a complication of PTPA and died 2 days after the procedure. In the remaining 28 patients, PTPA did not produce immediate hemodynamic improvement at the time of the procedure. However, after follow-up (6.0+/-6.9 months), New York Heart Association functional classifications and levels of plasma B-type natriuretic peptide significantly improved (both P