Effects of Ginkgo biloba extract (EGb 761) on learning and possible actions on aging
Effects of Ginkgo biloba extract (EGb 761) on learning and possible actions on aging
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DOI：
10.1016/s0928-4257(97)82409-6
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发表时间：
1997-12-01
影响因子：
--
通讯作者：
Chapouthier, G
中科院分区：
文献类型：
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作者：
Cohen-Salmon, C;Venault, P;Chapouthier, G
银杏叶提取物（EGb 761）的效果研究表明，对成年和老年瑞士小鼠的训练有增强作用。对近交系小鼠的分析证实了这种对EGb 761的敏感性，但取决于品系，在不同年龄有不同的影响。最有趣的结果与DBA/2 J品系老年小鼠观察到的性能改善有关。在海马苔藓纤维的研究中，用近交系获得的结果使我们有可能提出训练改善与海马组织结构之间的联系。这种可能性，这可以通过进一步的研究证实，在这里提出。
A study of the effect of Ginkgo biloba extract (EGb 761) has shown enhancing effects on training in adult and aged Swiss mice. An analysis of inbred mice has confirmed this sensitivity to EGb 761, but depending on the strains, with different effects at different ages. The most interesting results are related to improvements in performances observed with aged mice of the DBA/2J strain. The results obtained with inbred strains in the study of the mossy fibers of the hippocampus make it possible to suggest a link between the improvements in training and the histological structure of the hippocampus. This possibility, which can be confirmed by further studies, is presented here.