Stress and quality of life in the renal transplant patient: A preliminary investigation

Stress and quality of life in the renal transplant patient: A preliminary investigation
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DOI:
10.1046/j.1365-2648.1997.1997025562.x
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发表时间:
1997-03-01
影响因子:
3.8
通讯作者:
Wainwright, SP
Wainwright, SP
中科院分区:
医学3区
文献类型:
--
作者:
Fallon, M;Gould, D;Wainwright, SP

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终末期肾病是一种慢性疾病,会缩短患者的寿命,目前尚无治愈方法,目前许多患者选择的治疗方法肾移植可能会带来许多缺点:持续的排斥风险,特别是在前六个月,需要遵守复杂的药物治疗方案吗?产生明显的副作用以及需要持续的医疗监督。尽管存在这些问题,但对肾移植后患者的研究却很少。本文报道的小规模探索性研究的目的是探讨患者在第一次功能正常的肾移植后的不同阶段对压力和生活质量的看法:六个月内、一到五年之间以及五年以上(每组 n = 10)。从结果中可以明显看出,患者有很多担忧,其中最常提到的是对拒绝的恐惧,其次是产品中身体形象改变所产生的压力。免疫抑制治疗)。尽管如此,所有研究都报告移植后生活质量显着提高,尽管中间组(手术后 1-5 年)患者的改善最不明显,他们也经历了最大的压力,建议进行更大规模的研究。提高研究结果的有效性,临床医生可以使用这些结果来设计患者干预措施,以提高护理质量和生活质量。
End-stage renal disease is a chronic condition which reduces the Life-span of its victims, At present there is no cure, Renal transplantation, currently the treatment of choice for many patients, is potentially associated with a number of drawbacks: constant risk of rejection, especially during the first six months, the need to comply with a complex regime of medication capable? of producing pronounced side-effects and the need for ongoing medical supervision. Despite these problems, little research has been undertaken with patients following renal transplantation, The aim of the small-scale, exploratory study reported here was to explore patients' perceptions of stress and quality of life at different stages following a first, functioning renal graft: within six months, between one and five years and over five years later (n = 10 in each group). From the results it became apparent that patients had a number of concerns, of which fear of rejection was the most frequently mentioned, followed by stress generated through altered body image Ia product. of immunosuppressive therapy). Nevertheless, all reported a significant increase in quality of life after transplantation, although improvement was least marked in patients in the intermediate group (1-5 years after surgery) who also experienced most stress, A larger scale study is recommended. to increase the validity of findings which clinicians could then use to design patient interventions to enhance quality of care and quality of life.