Microvascular invasion in cancer of the oral cavity and oropharynx.
Microvascular invasion in cancer of the oral cavity and oropharynx.
复制标题
口腔和口咽癌的微血管侵犯。
DOI：
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
S. Schaefer
中科院分区：
文献类型：
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作者：
L. Close;D. Burns;J. Reisch;S. Schaefer
The presence of squamous cell carcinoma within capillaries and/or venules in the immediate vicinity of primary lesions of the oral cavity and oropharynx may be related to regional lymph node metastasis. To evaluate this possibility, we have reviewed the clinical and histopathologic features of 43 consecutive cases of previously untreated T2 or greater squamous cell carcinoma of these sites managed with simultaneous surgical treatment of the primary neoplasm and the neck. The incidence of histologically proved cervical metastasis for all lesions with vascular invasion compared with those without vascular involvement was highly significant. No statistical correlation was found for the clinical stage of neck disease or for the other pathologic features of the primary tumor, ie, size, appearance, differentiation, depth of invasion, periphery of lesion, inflammatory infiltrate, and perineural invasion, when compared with the histopathologic status of regional lymph nodes.
