Intraday glucose fluctuation is common in preterm infants receiving intermittent tube feeding
Intraday glucose fluctuation is common in preterm infants receiving intermittent tube feeding
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DOI：
10.1111/ped.12838
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发表时间：
2016-05-01
影响因子：
1.4
通讯作者：
Hata, Daisuke
中科院分区：
文献类型：
--
作者：
Mizumoto, Hiroshi;Kawai, Masahiko;Hata, Daisuke
背景：我们先前报道了三例早产儿在达到完全肠道喂养后血糖异常。最近研究表明，临床稳定的早产儿在建立肠内营养后，血糖可能会出现较大波动。我们假设，早产儿日内血糖波动是一种常见的发现，但在足月后的概念年龄改善。方法：从2010年6月至2012年7月，13名早产儿（29.5 +/- 2.1后概念周，1144 +/- 319 g）参加了这项研究。连续葡萄糖监测（CGM）平均在受孕后33.5 ± 1.4周进行，在没有静脉葡萄糖供应的情况下，每3小时进行一次胃管喂养。
Background: We previously reported on three preterm infants with blood glucose abnormalities after reaching full enteral feeding. Recently, it has been shown that clinically stable preterm infants may have large fluctuations in blood glucose after the establishment of enteral nutrition. We hypothesized that intraday glucose fluctuation is a common finding in preterm infants, but improves at term post-conceptual age. This report describes a case series.Methods: From June 2010 to July 2012, 13 preterm infants (29.5 +/- 2.1 post-conceptual weeks, 1144 +/- 319 g) were enrolled in this study. Continuous glucose monitoring (CGM) was conducted on average at 33.5 +/- 1.4 post-conceptual weeks, when they received gastric tube feeding every 3 h in the absence of i.v. glucose supply.Results: Eight infants (62%) had large intraday glucose fluctuation with repeated hyperglycemic (>150 mg/dL) and hypoglycemic (