Suppression of Oral Sweet Sensations during Consumption of Sweet Food in Humans: Effects on Gastric Emptying Rate, Glycemic Response, Appetite, Food Satisfaction and Desire for Basic Tastes
Suppression of Oral Sweet Sensations during Consumption of Sweet Food in Humans: Effects on Gastric Emptying Rate, Glycemic Response, Appetite, Food Satisfaction and Desire for Basic Tastes
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DOI：
10.3390/nu12051249
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发表时间：
2020-05-01
期刊：
影响因子：
5.9
通讯作者：
Kashima, Hideaki
中科院分区：
文献类型：
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作者：
Kashima, Naomi;Kimura, Kanako;Kashima, Hideaki
口腔甜味感觉抑制（OSS）由于较低的喜好而急剧减少甜味食物的摄入。然而，很少有人知道其他的生理反应，在餐时和餐后阶段。在这里，我们探讨了匙羹藤（GS）为基础的抑制OSS的几种类型的甜味食物（松饼，甜酸奶，香蕉）的胃排空，血糖（BG），血浆胰岛素（PI），食欲指数（饥饿，丰满和预期消费），满意度和欲望的味道。15名健康受试者（22 +/- 3岁，9名女性）参加了研究。受试者在吃甜味食物前用GS溶液或蒸馏水漱口。与用蒸馏水冲洗相比，受试者在食用每种食物后感觉到与GS冲洗相关的甜味强度降低和味觉喜好降低（p < 0.05）。与用蒸馏水冲洗相比，用GS冲洗在进餐期间和之后的胃排空、BG、PI和食欲指数没有显著变化（p > 0.05）。在餐后阶段，观察到GS冲洗对甜味的更高欲望以及更低的满意度（p < 0.05）。这些结果表明，OSS的抑制不影响胃排空，血糖反应和食欲期间和之后的消费甜味食物。
Suppression of oral sweet sensation (OSS) acutely reduces intake of sweet-tasting food due to lower liking. However, little is known about other physiological responses during both the prandial and postprandial phase. Here, we explored the effects of Gymnema sylvestre (GS)-based suppression of OSS of several types of sweet-tasting food (muffin, sweet yogurt, banana) on gastric emptying, blood glucose (BG), plasma insulin (PI), appetite indices (hunger, fullness and prospective consumption), satisfaction and desire for tastes. Fifteen healthy subjects (22 +/- 3 years, 9 women) took part in the study. Subjects rinsed their mouth with either GS solution or distilled water before eating the sweet-tasting food. Subjects felt decreased sweet taste intensity and reduced taste liking associated with GS rinsing after consuming each food, compared with rinsing with distilled water (p < 0.05). Gastric emptying, BG, PI and appetite indices during and after the prandial phase did not significantly change with GS rinsing compared to rinsing with distilled water (p > 0.05). Higher desire for sweet taste as well as lower satisfaction (p < 0.05) in the postprandial phase were observed with GS rinsing. These results suggest that the suppression of OSS does not affect gastric emptying, glycemic response and appetite during and after consumption of sweet-tasting food.