Patient dropout in assisted reproductive technology program: implications for pregnancy rates
Patient dropout in assisted reproductive technology program: implications for pregnancy rates
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DOI：
10.1016/s0015-0282(97)81515-4
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发表时间：
1997-08-01
影响因子：
6.7
通讯作者：
Evers, JLH
中科院分区：
文献类型：
--
作者：
Land, JA;Courtar, DA;Evers, JLH
目的：研究辅助生殖技术 (ART) 后患者的脱落率及其对粗妊娠率和累积妊娠率 (PR) 的影响。设计：回顾性队列研究。地点：大学医院三级护理生育诊所。患者：220 对申请第一个 ART 治疗周期的夫妇。主要结果指标：每个周期的脱落率和 PR、累积脱落率和累积妊娠率 PR.结果：三个治疗周期后，累计退出率为 202 例中的 126 例（62.4%）； 13.9% (n = 28) 是由于主动审查造成的。生命表分析表明，主动审查可以使累积 PR 更加平坦。结论：即使 ART 费用由医疗费用保险承担，ART 的退出率也很高。生命表分析高估了 ART 中的累积 PR。 (C) 1997 年，美国生殖医学学会。
Objective: To study patient dropout and its impact on crude and cumulative pregnancy rates (PRs) after assisted reproductive technology (ART).Design: Retrospective cohort study.Setting: University hospital-based tertiary care fertility clinic.Patient(s): Two hundred two couples applying for their first ART treatment cycle.Main Outcome Measure(s): Drop-out rate and PR per cycle, cumulative drop-out rate and cumulative PR.Result(s): After three treatment cycles, the cumulative drop-out rate was 126 of 202 (62.4%); 13.9% (n = 28) was due to active censoring. Active censoring was shown to flatter cumulative PRs by life-table analysis.Conclusion: Dropout from ART is high, even when ART costs are covered by health cost insurance. Life-table analysis overestimates cumulative PRs in ART. (C) 1997 by American Society for Reproductive Medicine.