Risk factors for the spread of HIV and other sexually transmitted infections among men who have sex with men infected with HIV in Lima, Peru.
Risk factors for the spread of HIV and other sexually transmitted infections among men who have sex with men infected with HIV in Lima, Peru.
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DOI：
10.1136/sti.2008.031310
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发表时间：
2008-11
影响因子：
3.6
通讯作者：
Coates, T. J.
中科院分区：
文献类型：
--
作者：
Clark, J. L.;Konda, K. A.;Segura, E. R.;Salvatierra, H. J.;Leon, S. R.;Hall, E. R.;Caceres, C. F.;Klausner, J. D.;Coates, T. J.
评估在秘鲁性病门诊就诊的男男性行为者（MSM）中性传播感染（STI）的患病率、性风险行为的频率以及HIV感染状况知识与性风险行为之间的关系。我们从秘鲁利马的一家市STI诊所招募了559名MSM作为便利样本。参与者完成了一项调查，并提供了用于HIV，梅毒和HSV-2抗体检测的血液，以及用于淋病和衣原体核酸检测的尿液。在124例HIV感染者中，72.6%的MSM知晓自己的HIV感染状况。活动性梅毒（RPR≥1：8）检出率为21.0%，单纯疱疹病毒2型（HSV-2）检出率为79.8%，尿道淋病检出率为1.6%，衣原体感染检出率为1.6%。在41名报告与最后一个性伴侣发生插入式肛交的参与者中，34.2%的人没有使用安全套。在86名报告接受性肛交的参与者中，25.6%的人没有使用安全套。33.6%（35/104）的参与者报告在过去6个月内与未感染HIV的伴侣至少发生过一次插入式无保护肛交（UAI），44.6%（45/101）的参与者报告与未感染HIV的伴侣发生过接受性UAI。在知晓自己血清状态的男性与先前未确诊的男性之间，未观察到与HIV未感染或HIV感染伴侣发生UAI的频率存在差异（所有p值>0.05）。秘鲁的HIV感染者从事传播HIV和STI的高危行为。艾滋病毒感染状况的知识与无保护的肛交频率降低无关。有必要在诊断出艾滋病毒感染后进一步努力减少危险行为。
To assess the prevalence of sexually transmitted infections (STIs), frequency of sexual risk behaviors, and relationship between knowledge of HIV infection status and sexual risk behavior among HIV-infected men who have sex with men (MSM) attending an STI clinic in Peru. We recruited a convenience sample of 559 MSM from a municipal STI clinic in Lima, Peru. Participants completed a survey and provided blood for HIV, Syphilis, and HSV-2 antibody testing, and urine for gonorrhea and chlamydia nucleic acid testing. Among 124 HIV-infected MSM, 72.6% were aware of their HIV-infected status. Active syphilis (RPR≥1:8) was diagnosed in 21.0% of HIV-infected participants, HSV-2 in 79.8%, urethral gonorrhea in 1.6%, and chlamydia in 1.6%. Among 41 participants reporting insertive anal intercourse with their last sex partner, 34.2% did not use a condom. Of 86 participants reporting receptive anal intercourse, 25.6% did not use a condom. At least one episode of insertive unprotected anal intercourse (UAI) with an HIV-uninfected partner during the previous six months was reported by 33.6% (35/104) of participants, and receptive UAI with an HIV-uninfected partner by 44.6% (45/101). No difference in frequency of UAI, with HIV-uninfected or HIV-infected partners, was observed between men who knew their serostatus compared with those who were previously undiagnosed (all p-values >0.05). HIV-infected MSM in Peru engaged in high-risk behaviors for spreading HIV and STIs. Knowledge of HIV-infected status was not associated with a decreased frequency of unprotected anal intercourse. Additional efforts to reduce risk behavior after the diagnosis of HIV infection are necessary.
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影响因子：
6.4
作者：
Lama, Javier R.;Lucchetti, Aldo;Sanchez, Jose L.
通讯作者：
Sanchez, Jose L.
影响因子：
168.9
作者：
Celum, Connie;Wald, Anna;Corey, Lawrence
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Corey, Lawrence
影响因子：
4.4
作者：
Caceres, Carlos F.;Konda, Kelika A.;Coates, Thomas J.
通讯作者：
Coates, Thomas J.
影响因子：
3.1
作者：
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通讯作者：
Elford, Jonathan
影响因子：
2.2
作者：
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