Comparison of the Clinical Outcomes between Echelette Extended Range of Vision and Diffractive Bifocal Intraocular Lenses
Comparison of the Clinical Outcomes between Echelette Extended Range of Vision and Diffractive Bifocal Intraocular Lenses
复制标题
小阶梯光栅大视野人工晶状体与衍射双焦点人工晶状体的临床效果比较
DOI：
10.1155/2019/5815040
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发表时间：
2019-09-23
影响因子：
1.9
通讯作者：
Yao, Ke
中科院分区：
文献类型：
--
作者：
Liu, Xin;Song, Xiaohui;Yao, Ke
目的比较小阶梯光栅增视镜与衍射双焦点人工晶状体的临床效果。方法本研究为前瞻性、连续性、非随机临床试验。73例（109只眼）合格患者接受了小阶梯ERV IOL（Tecnis Symfony ZXR 00）或衍射双焦点IOL（Tecnis ZMB 00）植入。术后1周、1个月、3个月分别检查不同距离的视力。在3个月时，散焦曲线，对比敏感度（CS）与眩光，光程差（OPD）扫描和问卷进行了评价。回归分析术后视力的影响因素。结果ZXR 00的远视力和中视力均优于ZMB 00（P < 0.001），远矫正近视力优于ZXR 00（P <0.05）。多因素分析显示，眼轴长越长，ZMB 00的中位视力（P < 0.001）和近视力（P=0.013）越差。ZXR 00表现出更平滑的散焦曲线和更高的CS。ZXR 00上级调制传递函数（MTF）和Strehl比均高于其他两组（P < 0.05）。在问卷评估中，ZXR 00在自报视力、视觉功能-14（VF-14）问卷、视觉质量（QoV）问卷、满意度和推荐等级方面获得了更好的结果。ZXR 00和ZMB 00之间的特异性依赖性在统计学上没有差异。结论ZXR 00在远视力、中间视力、离焦曲线平滑度、CS和视觉舒适度方面效果显著，而ZMB 00在近视力方面效果更好。如果术后SE仍为轻度阴性，ZXR 00可获得更好的近视力。眼轴长度相对较长的患者在植入ZMB 00后可能获得较差的中间视力和近视力。本试验注册于ChiCTR-ONC-17011119。
Purpose To compare the clinical outcomes of echelette extended range of vision (ERV) and diffractive bifocal intraocular lenses (IOLs). Methods This is a prospective, consecutive, nonrandomized clinical trial. Seventy-three eligible patients (109 eyes) received the implantation of echelette ERV IOL (Tecnis Symfony ZXR00) or diffractive bifocal IOL (Tecnis ZMB00). 1 week, 1 month, and 3 months after surgery, visual acuities at different distances were examined. At 3 months, defocus curves, contrast sensitivities (CSs) with and without glare, optic path difference (OPD) scans, and questionnaires were evaluated. Regression analyses were applied to discover influence factors on postoperative vision. Results ZXR00 showed better distance (P < 0.05) and intermediate (P < 0.001) visual acuities, while ZMB00 was better at distance-corrected near visual acuity (P < 0.001). Multivariate analyses indicated that worse intermediate (P < 0.001) and near vision (P=0.013) of ZMB00 might occur in patients with longer axial length. ZXR00 demonstrated smoother defocus curve and higher CSs. Superior modulation transfer function (MTF) and higher Strehl ratio (P < 0.05) were shown in ZXR00. In questionnaire evaluation, ZXR00 received better outcomes in self-reported vision, Visual Function-14 (VF-14) questionnaire, Quality of Vision (QoV) questionnaire, satisfaction, and recommendation grades. Spectacle dependence did not differ between ZXR00 and ZMB00 statistically. Conclusion ZXR00 proved to be remarkable in distance and intermediate vision, defocus curve smoothness, CSs, and visual comfort, while ZMB00 achieved better near vision. ZXR00 may attain better near vision if postoperative SE remains slightly negative. Patients with relatively longer axial length might receive less favorable intermediate and near vision after ZMB00 implantation. This trial is registered with ChiCTR-ONC-17011119.